Botulinum toxin in the treatment of vocal fold nodules

Jacqui E. Allen, Peter C Belafsky

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose of review: Promising new techniques in the management of vocal fold nodules have been developed in the past 2 years. Simultaneously, the therapeutic use of botulinum toxin has rapidly expanded. This review explores the use of botulinum toxin in treatment of vocal nodules and summarizes current therapeutic concepts. Recent findings: New microsurgical instruments and techniques, refinements in laser technology, radiosurgical excision and steroid intralesional injections are all promising new techniques in the management of vocal nodules. Botulinum toxin-induced 'voice rest' is a new technique we have employed in patients with recalcitrant nodules. Successful resolution of nodules is possible with this technique, without the risk of vocal fold scarring inherent in dissection/excision techniques. Botulinum toxin usage is exponentially increasing, and large-scale, long-term studies demonstrate its safety profile. Summary: Targeted vocal fold temporary paralysis induced by botulinum toxin injection is a new, well tolerated and efficacious treatment in patients with persistent vocal fold nodules.

Original languageEnglish (US)
Pages (from-to)427-430
Number of pages4
JournalCurrent Opinion in Otolaryngology and Head and Neck Surgery
Volume17
Issue number6
DOIs
StatePublished - Dec 2009

Fingerprint

Botulinum Toxins
Vocal Cords
Intralesional Injections
Therapeutics
Therapeutic Uses
Paralysis
Cicatrix
Dissection
Lasers
Steroids
Technology
Safety
Injections

Keywords

  • Botox
  • Botulinum toxin
  • Vocal nodules

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

Botulinum toxin in the treatment of vocal fold nodules. / Allen, Jacqui E.; Belafsky, Peter C.

In: Current Opinion in Otolaryngology and Head and Neck Surgery, Vol. 17, No. 6, 12.2009, p. 427-430.

Research output: Contribution to journalArticle

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