Border disease like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses

Bennie Osburn, G. L. Clarke, W. C. Stewart, M. Sawyer

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Serum samples were collected from fetal and newborn lambs with a naturally occurring border disease like syndrome and from lambs inoculated with brainspleen suspensions obtained from affected lambs. Serum neutralization (SN) tests for antibodies to bovine viral diarrhea (BVD) and hog cholera viruses and the single radial immunodiffusion assay for quantitating immunoglobulin G (IgG) were performed. In precolostral samples, serum IgG content was less than 0.10 mg./ml. in control lambs and ranged from 0.10 to 1.1 mg./ml. in affected lambs; postcolostral values exceeded 7.5 mg./ml. Serum neutralizing antibodies to hog cholera were detected in all of 13 samples examined, the titers ranging from 1:4 to 1:1,024. Serum neutralizing antibodies to BVD were found in 8 of 13 samples that had titers to hog cholera.

Original languageEnglish (US)
Pages (from-to)1165-1167
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume163
Issue number10
StatePublished - Dec 1 1973

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Border disease like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses'. Together they form a unique fingerprint.

  • Cite this