Bone mineral density of the lumbar spine in women with endometriosis

Nancy E Lane, J. Baptista, E. Orwoll

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Young women with endometriosis have reduced cortical and trabecular bone mineral density of the wrist compared with age-matched controls. This conclusion was based on 41 subjects from one geographical location. The purpose of this study was to test this finding in a larger, more geographically diverse population. One hundred women with laparoscopically proven endometriosis were enrolled in this study for the evaluation of the efficacy of nafarelin, a gonadotropin-releasing hormone agonist. Patients were recruited from nine investigators across the United States and Canada, and bone mineral density of the lumbar spine was obtained at baseline, with 6 Hologic QDR (Hologic Inc., Waltham, MA) and a Lunar DPX (Lunar Radiation Corp., Madison, WI) instrument. The age of the women was 30.3 ± 5.8 years (mean ± SD); 91% were white. Bone mineral density of the lumbar spine was 1.1 ± 0.11 g/cm2 (n = 85 Hologic QDR) and 1.2 ± 0.93 g/cm2 (n = 15 Lunar DPX). Hologic bone mineral density was 104.8 ± 11.0 and Lunar bone mineral density was 103.4% ± 7.8% of normal values for age. To conclude, in a population based cross-sectional study of patients with endometriosis, we do not observe low bone mineral density of the lumbar spine by techniques that measure a combination of cortical and trabecular bone.

Original languageEnglish (US)
Pages (from-to)537-542
Number of pages6
JournalFertility and Sterility
Volume55
Issue number3
StatePublished - 1991
Externally publishedYes

Fingerprint

Endometriosis
Bone Density
Spine
Nafarelin
Wrist
Gonadotropin-Releasing Hormone
Population
Canada
Reference Values
Cross-Sectional Studies
Research Personnel
Radiation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Bone mineral density of the lumbar spine in women with endometriosis. / Lane, Nancy E; Baptista, J.; Orwoll, E.

In: Fertility and Sterility, Vol. 55, No. 3, 1991, p. 537-542.

Research output: Contribution to journalArticle

Lane, NE, Baptista, J & Orwoll, E 1991, 'Bone mineral density of the lumbar spine in women with endometriosis', Fertility and Sterility, vol. 55, no. 3, pp. 537-542.
Lane, Nancy E ; Baptista, J. ; Orwoll, E. / Bone mineral density of the lumbar spine in women with endometriosis. In: Fertility and Sterility. 1991 ; Vol. 55, No. 3. pp. 537-542.
@article{033cdf35dc9f4d5d90d9677cde2d97de,
title = "Bone mineral density of the lumbar spine in women with endometriosis",
abstract = "Young women with endometriosis have reduced cortical and trabecular bone mineral density of the wrist compared with age-matched controls. This conclusion was based on 41 subjects from one geographical location. The purpose of this study was to test this finding in a larger, more geographically diverse population. One hundred women with laparoscopically proven endometriosis were enrolled in this study for the evaluation of the efficacy of nafarelin, a gonadotropin-releasing hormone agonist. Patients were recruited from nine investigators across the United States and Canada, and bone mineral density of the lumbar spine was obtained at baseline, with 6 Hologic QDR (Hologic Inc., Waltham, MA) and a Lunar DPX (Lunar Radiation Corp., Madison, WI) instrument. The age of the women was 30.3 ± 5.8 years (mean ± SD); 91{\%} were white. Bone mineral density of the lumbar spine was 1.1 ± 0.11 g/cm2 (n = 85 Hologic QDR) and 1.2 ± 0.93 g/cm2 (n = 15 Lunar DPX). Hologic bone mineral density was 104.8 ± 11.0 and Lunar bone mineral density was 103.4{\%} ± 7.8{\%} of normal values for age. To conclude, in a population based cross-sectional study of patients with endometriosis, we do not observe low bone mineral density of the lumbar spine by techniques that measure a combination of cortical and trabecular bone.",
author = "Lane, {Nancy E} and J. Baptista and E. Orwoll",
year = "1991",
language = "English (US)",
volume = "55",
pages = "537--542",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Bone mineral density of the lumbar spine in women with endometriosis

AU - Lane, Nancy E

AU - Baptista, J.

AU - Orwoll, E.

PY - 1991

Y1 - 1991

N2 - Young women with endometriosis have reduced cortical and trabecular bone mineral density of the wrist compared with age-matched controls. This conclusion was based on 41 subjects from one geographical location. The purpose of this study was to test this finding in a larger, more geographically diverse population. One hundred women with laparoscopically proven endometriosis were enrolled in this study for the evaluation of the efficacy of nafarelin, a gonadotropin-releasing hormone agonist. Patients were recruited from nine investigators across the United States and Canada, and bone mineral density of the lumbar spine was obtained at baseline, with 6 Hologic QDR (Hologic Inc., Waltham, MA) and a Lunar DPX (Lunar Radiation Corp., Madison, WI) instrument. The age of the women was 30.3 ± 5.8 years (mean ± SD); 91% were white. Bone mineral density of the lumbar spine was 1.1 ± 0.11 g/cm2 (n = 85 Hologic QDR) and 1.2 ± 0.93 g/cm2 (n = 15 Lunar DPX). Hologic bone mineral density was 104.8 ± 11.0 and Lunar bone mineral density was 103.4% ± 7.8% of normal values for age. To conclude, in a population based cross-sectional study of patients with endometriosis, we do not observe low bone mineral density of the lumbar spine by techniques that measure a combination of cortical and trabecular bone.

AB - Young women with endometriosis have reduced cortical and trabecular bone mineral density of the wrist compared with age-matched controls. This conclusion was based on 41 subjects from one geographical location. The purpose of this study was to test this finding in a larger, more geographically diverse population. One hundred women with laparoscopically proven endometriosis were enrolled in this study for the evaluation of the efficacy of nafarelin, a gonadotropin-releasing hormone agonist. Patients were recruited from nine investigators across the United States and Canada, and bone mineral density of the lumbar spine was obtained at baseline, with 6 Hologic QDR (Hologic Inc., Waltham, MA) and a Lunar DPX (Lunar Radiation Corp., Madison, WI) instrument. The age of the women was 30.3 ± 5.8 years (mean ± SD); 91% were white. Bone mineral density of the lumbar spine was 1.1 ± 0.11 g/cm2 (n = 85 Hologic QDR) and 1.2 ± 0.93 g/cm2 (n = 15 Lunar DPX). Hologic bone mineral density was 104.8 ± 11.0 and Lunar bone mineral density was 103.4% ± 7.8% of normal values for age. To conclude, in a population based cross-sectional study of patients with endometriosis, we do not observe low bone mineral density of the lumbar spine by techniques that measure a combination of cortical and trabecular bone.

UR - http://www.scopus.com/inward/record.url?scp=0026065117&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026065117&partnerID=8YFLogxK

M3 - Article

C2 - 2001755

AN - SCOPUS:0026065117

VL - 55

SP - 537

EP - 542

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 3

ER -