Abstract
Parvoviruses in the genera Bocaparvovirus (HBoV), Erythroparvovirus (B19) and Tetraparvovirus (PARV4) are the only autonomous parvoviruses known to be associated with human and non-human primates based on studies and clinical cases in humans worldwide and non-human primates in Asia and Africa. Here, the presence of these agents with pathogenic potential was assessed by PCR in blood and faeces from 55 howler monkeys, 112 white-face monkeys, 3 squirrel monkeys and 127 spider monkeys in Costa Rica and El Salvador. Overall, 3.7% (11/297) of the monkeys had HboV DNA, 0.67% (2/297) had B19 DNA, and 14.1% (42/297) had PARV4 DNA, representing the first detection of these viruses in New World Primates (NWP). Sex was significantly associated with the presence of HBoV, males having greater risk up to nine times compared with females. Captivity was associated with increased prevalence for PARV4 and when all viruses were analysed together. This study provides compelling molecular evidence of parvoviruses in NWPs and underscores the importance of future research aimed at understanding how these viruses behave in natural environments of the Neotropics and what variables may favour their presence and transmission.
| Original language | English (US) |
|---|---|
| Journal | Transboundary and Emerging Diseases |
| DOIs | |
| State | Accepted/In press - Jan 1 2019 |
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Keywords
- B19
- HBoV
- new world primates
- non-human primates
- PARV4
- primate(s) parvovirus
ASJC Scopus subject areas
- Immunology and Microbiology(all)
- veterinary(all)
Cite this
Bocaparvovirus, Erythroparvovirus and Tetraparvovirus in New World Primates from Central America. / Chaves, Andrea; Ibarra-Cerdeña, Carlos N.; López-Pérez, Andrés M.; Monge, Otto; Avendaño, Roberto; Ureña-Saborio, Hilary; Chavarría, Max; Zaldaña, Karla; Sánchez, Lucía; Ortíz-Malavassi, Edgar; Suzan, Gerardo; Foley, Janet; Gutiérrez-Espeleta, Gustavo A.
In: Transboundary and Emerging Diseases, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bocaparvovirus, Erythroparvovirus and Tetraparvovirus in New World Primates from Central America
AU - Chaves, Andrea
AU - Ibarra-Cerdeña, Carlos N.
AU - López-Pérez, Andrés M.
AU - Monge, Otto
AU - Avendaño, Roberto
AU - Ureña-Saborio, Hilary
AU - Chavarría, Max
AU - Zaldaña, Karla
AU - Sánchez, Lucía
AU - Ortíz-Malavassi, Edgar
AU - Suzan, Gerardo
AU - Foley, Janet
AU - Gutiérrez-Espeleta, Gustavo A.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Parvoviruses in the genera Bocaparvovirus (HBoV), Erythroparvovirus (B19) and Tetraparvovirus (PARV4) are the only autonomous parvoviruses known to be associated with human and non-human primates based on studies and clinical cases in humans worldwide and non-human primates in Asia and Africa. Here, the presence of these agents with pathogenic potential was assessed by PCR in blood and faeces from 55 howler monkeys, 112 white-face monkeys, 3 squirrel monkeys and 127 spider monkeys in Costa Rica and El Salvador. Overall, 3.7% (11/297) of the monkeys had HboV DNA, 0.67% (2/297) had B19 DNA, and 14.1% (42/297) had PARV4 DNA, representing the first detection of these viruses in New World Primates (NWP). Sex was significantly associated with the presence of HBoV, males having greater risk up to nine times compared with females. Captivity was associated with increased prevalence for PARV4 and when all viruses were analysed together. This study provides compelling molecular evidence of parvoviruses in NWPs and underscores the importance of future research aimed at understanding how these viruses behave in natural environments of the Neotropics and what variables may favour their presence and transmission.
AB - Parvoviruses in the genera Bocaparvovirus (HBoV), Erythroparvovirus (B19) and Tetraparvovirus (PARV4) are the only autonomous parvoviruses known to be associated with human and non-human primates based on studies and clinical cases in humans worldwide and non-human primates in Asia and Africa. Here, the presence of these agents with pathogenic potential was assessed by PCR in blood and faeces from 55 howler monkeys, 112 white-face monkeys, 3 squirrel monkeys and 127 spider monkeys in Costa Rica and El Salvador. Overall, 3.7% (11/297) of the monkeys had HboV DNA, 0.67% (2/297) had B19 DNA, and 14.1% (42/297) had PARV4 DNA, representing the first detection of these viruses in New World Primates (NWP). Sex was significantly associated with the presence of HBoV, males having greater risk up to nine times compared with females. Captivity was associated with increased prevalence for PARV4 and when all viruses were analysed together. This study provides compelling molecular evidence of parvoviruses in NWPs and underscores the importance of future research aimed at understanding how these viruses behave in natural environments of the Neotropics and what variables may favour their presence and transmission.
KW - B19
KW - HBoV
KW - new world primates
KW - non-human primates
KW - PARV4
KW - primate(s) parvovirus
UR - http://www.scopus.com/inward/record.url?scp=85073955315&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85073955315&partnerID=8YFLogxK
U2 - 10.1111/tbed.13357
DO - 10.1111/tbed.13357
M3 - Article
C2 - 31529612
AN - SCOPUS:85073955315
JO - Transboundary and Emerging Diseases
JF - Transboundary and Emerging Diseases
SN - 1865-1674
ER -