Blood parameters and immune status of rainbow trout with proliferative kidney disease

J. Scott Foott, Ronald P. Hedrick

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16 Scopus citations


Blood parameters, disease resistance, and the immune response were sequentially evaluated in rainbow trout Oncorhynchus mykiss with proliferative kidney disease (PKD). The fish were maintained under laboratory conditions, and the study group went through a full cycle of the disease. Hematological and serological changes occurred primarily in those fish with severe kidney lesions. Fish infected with the parasite that causes PKD demonstrated a greater resistance to bacterial challenge, and their immune responses were heightened when compared with those of uninfected fish. These data suggest that PKD alone is not a predisposing factor for secondary infections if the fish does not incur severe renal lesions.

Original languageEnglish (US)
Pages (from-to)141-148
Number of pages8
JournalJournal of Aquatic Animal Health
Issue number2
StatePublished - Jan 1 1990


ASJC Scopus subject areas

  • Aquatic Science

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