Blood flow into brown fat of rats is greater after a high carbohydrate than after a high fat test meal

Z. Glick, S. J. Wickler, J. S. Stern, Barbara A Horwitz

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Postprandial oxygen uptake of whole animals and rate of blood flow into the scapular and cervical brown adipose tissue (BAT) of Osborne-Mendel male rats (200 g) were compared for those receiving a high carbohydrate meal or an equicaloric high fat meal. Blood flow was determined by the use of radiolabeled microspheres injected into the left ventricle of anesthetized animals, 2-3 hours after the test meal. In vivo oxygen uptake was elevated by about 10% (P < 0.05) and blood flow by more than 100% (P < 0.05) in the group receiving the high carbohydrate meal compared to the high fat meal. The rate of blood flow into tissues other than brown fat was not significantly altered by the composition of the test meal. These tissues included heart, gastrocnemius and soleus muscles, GI tract and white adipose tissue. Our data suggest that a high carbohydrate meal is more thermogenic than a high fat meal, and that the difference in the magnitude of thermic effect produced by the two meals is paralleled by a corresponding difference in brown fat thermogenesis.

Original languageEnglish (US)
Pages (from-to)1934-1939
Number of pages6
JournalJournal of Nutrition
Volume114
Issue number10
StatePublished - 1984

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test meals
Brown Adipose Tissue
brown adipose tissue
blood flow
Meals
Fats
Carbohydrates
carbohydrates
rats
lipids
uptake mechanisms
oxygen
white adipose tissue
heat production
gastrointestinal system
animals
heart
Skeletal Muscle
heat
muscles

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Glick, Z., Wickler, S. J., Stern, J. S., & Horwitz, B. A. (1984). Blood flow into brown fat of rats is greater after a high carbohydrate than after a high fat test meal. Journal of Nutrition, 114(10), 1934-1939.

Blood flow into brown fat of rats is greater after a high carbohydrate than after a high fat test meal. / Glick, Z.; Wickler, S. J.; Stern, J. S.; Horwitz, Barbara A.

In: Journal of Nutrition, Vol. 114, No. 10, 1984, p. 1934-1939.

Research output: Contribution to journalArticle

Glick, Z, Wickler, SJ, Stern, JS & Horwitz, BA 1984, 'Blood flow into brown fat of rats is greater after a high carbohydrate than after a high fat test meal', Journal of Nutrition, vol. 114, no. 10, pp. 1934-1939.
Glick, Z. ; Wickler, S. J. ; Stern, J. S. ; Horwitz, Barbara A. / Blood flow into brown fat of rats is greater after a high carbohydrate than after a high fat test meal. In: Journal of Nutrition. 1984 ; Vol. 114, No. 10. pp. 1934-1939.
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