Abstract
We report the delivery of quantum dot (QD) fluorescence probes into mammalian cells by electroporation and endocytosis. The pH sensitivity of mercaptoacetic-acid-capped CdSe/ZnSe/ZnS quantum dots (MAA QDs) was investigated in both solution and living cells, demonstrating the potential of QDs as an intracellular pH sensor with long-term photostability and limited photobleaching. Further, QDs were utilized to enhance the effects of nanosecond electric pulses (nanoelectropulses) on malignant cells. Nanoelectropulse treatment is a developing technique for cancer therapy by inducing programmed cell death (apoptosis) of cancer cells, while the introduction of semiconductor particles could modify the electric characterization of biological cells.
Original language | English (US) |
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Title of host publication | Conference Record of the International Power Modulator Symposium and High Voltage Workshop |
Pages | 570-572 |
Number of pages | 3 |
DOIs | |
State | Published - 2006 |
Event | 2006 IEEE International Power Modulator Conference, IPMC(27th Power Modulator Symposium and 2006 High Voltage Workshop) - Washington, DC, United States Duration: May 14 2006 → May 18 2006 |
Other
Other | 2006 IEEE International Power Modulator Conference, IPMC(27th Power Modulator Symposium and 2006 High Voltage Workshop) |
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Country/Territory | United States |
City | Washington, DC |
Period | 5/14/06 → 5/18/06 |
ASJC Scopus subject areas
- Engineering(all)