Biomechanical topography of human ankle cartilage

K. A. Athanasiou, G. G. Niederauer, R. C. Schenck

Research output: Contribution to journalArticle

132 Citations (Scopus)

Abstract

The material properties of normal cadaveric human cartilage in the ankle mortice (tibiotalar articulation) were evaluated to determine a possible etiologic mechanism of cartilage injury of the ankle when an obvious traumatic episode is not present. Using an automated indentation apparatus and the biphasic creep indentation methodology, creep indentation experiments were performed in five sites in the distal tibia, one site in the distal fibula, and eight sites in the proximal talus of 14 human ankles (seven pairs). Results showed significant differences in the mechanical properties of specific human ankle cartilage regions. Topographically, tibial cartilage is stiffer (1. 19 MPa) than talar cartilage (1.06 MPa). Cartilage in the anterior medial portion of the tibia has the largest aggregate modulus (HA=1.34 MPa), whereas the softest tissue was found to be in the posterior lateral (0.92 MPa) and the posterior medial (0.92 MPa) regions of the talus. The posterior lateral ridge of the talus was the thickest (1.45 mm) and the distal fibula was the thinnest (0.95 mm) articular cartilage. The largest Poisson's ratio was found in the distal fibula (0.08). The lowest and highest permeability were found in the anterior lateral regions of the astragalus (0.80 × 10-15 m4N-1sec-1) and the posterior medial region of the tibia (1.79 × 10-15 m4N-1sec-1), respectively. The anterior and posterior regions of the lateral and medial sites of the tibia were found to be 18-37% stiffer than the anatomically corresponding sites in the talus. The biomechanical results may explain clinically observed talar dome osteochondral lesions when no obvious traumatic event is present. Cartilage lesions in a repetitive overuse process in the ankle joint may be related to a disparity of mechanical properties between the articulating surfaces of the tibial and talar regions.

Original languageEnglish (US)
Pages (from-to)697-704
Number of pages8
JournalAnnals of Biomedical Engineering
Volume23
Issue number5
DOIs
StatePublished - Sep 1995
Externally publishedYes

Fingerprint

Cartilage
Topography
Indentation
Creep
Mechanical properties
Domes
Poisson ratio
Materials properties
Tissue

Keywords

  • Articular cartilage
  • Creep indentation
  • KLM biphasic theory
  • Material properties
  • Tibiotalar joint

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Athanasiou, K. A., Niederauer, G. G., & Schenck, R. C. (1995). Biomechanical topography of human ankle cartilage. Annals of Biomedical Engineering, 23(5), 697-704. https://doi.org/10.1007/BF00000016

Biomechanical topography of human ankle cartilage. / Athanasiou, K. A.; Niederauer, G. G.; Schenck, R. C.

In: Annals of Biomedical Engineering, Vol. 23, No. 5, 09.1995, p. 697-704.

Research output: Contribution to journalArticle

Athanasiou, KA, Niederauer, GG & Schenck, RC 1995, 'Biomechanical topography of human ankle cartilage', Annals of Biomedical Engineering, vol. 23, no. 5, pp. 697-704. https://doi.org/10.1007/BF00000016
Athanasiou, K. A. ; Niederauer, G. G. ; Schenck, R. C. / Biomechanical topography of human ankle cartilage. In: Annals of Biomedical Engineering. 1995 ; Vol. 23, No. 5. pp. 697-704.
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