Biomechanical Effects of Human Lumbar Discography

Kristen E. Lipscomb, Nesrin Sarigul-Klijn, Eric Klineberg, Vivek Mohan

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Study Design: An experimental and computational finite element analysis of human lumbar spine discography and its resulting effects on disk biomechanics. Objective: To characterize the changes in stress and displacement of the human lumbar spine disks after puncture due to discography. Summary of Background Data: Discography of the intervertebral disk (IVD) may be used to diagnose pathology of the disk and determine whether it may be a source for chronic back pain. It has recently been suggested that discography may lead to IVD degeneration, and has been a cause of controversy among spine care physicians. Materials and Methods: Both in vivo experiment using cadaveric specimens and a finite element model of the same L3-L5 lumbar spine was developed using computed tomography scans. Discography was simulated in the model as an area in the disk affected by needle puncture. The material properties in the nucleus pulposus were adjusted to match experimental data both before and after puncture. Results: Puncture of the IVD leads to increased deformation and increased stresses in the annulus fibrosis region of the disk. Pressure in the nucleus pulposus was found to decrease after puncture. Experimental and computational results correlated well. Conclusions: Puncturing the IVD changes disk biomechanics and hence may lead to progressive spine degenerations in particular in the punctured disks.

Original languageEnglish (US)
Pages (from-to)E219-E225
JournalClinical Spine Surgery
Volume30
Issue number3
DOIs
StatePublished - 2017

Fingerprint

Punctures
Spine
Intervertebral Disc
Biomechanical Phenomena
Intervertebral Disc Degeneration
Finite Element Analysis
Back Pain
Chronic Pain
Needles
Fibrosis
Research Design
Tomography
Pathology
Physicians
Pressure
Nucleus Pulposus

Keywords

  • discography
  • finite element analysis
  • lumbar spine biomechanics

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology

Cite this

Biomechanical Effects of Human Lumbar Discography. / Lipscomb, Kristen E.; Sarigul-Klijn, Nesrin; Klineberg, Eric; Mohan, Vivek.

In: Clinical Spine Surgery, Vol. 30, No. 3, 2017, p. E219-E225.

Research output: Contribution to journalArticle

Lipscomb, Kristen E. ; Sarigul-Klijn, Nesrin ; Klineberg, Eric ; Mohan, Vivek. / Biomechanical Effects of Human Lumbar Discography. In: Clinical Spine Surgery. 2017 ; Vol. 30, No. 3. pp. E219-E225.
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