Biomarkers of Helicobacter pylori-associated gastric cancer.

Cara L. Cooke, Javier Torres, Jay V Solnick

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Helicobacter pylori-associated gastric cancer is a major cause of morbidity and mortality worldwide, and is predicted to become even more common in developing countries as the population ages. Since gastric cancer develops slowly over years to decades, and typically progresses though a series of well-defined histologic stages, cancer biomarkers have potential to identify asymptomatic individuals in whom surgery might be curative, or even those for whom antibiotics to eradicate H. pylori could prevent neoplastic transformation. Here we describe some of the challenges of biomarker discovery, summarize current approaches to biomarkers of gastric cancer, and explore some recent novel strategies.

Original languageEnglish (US)
Pages (from-to)532-540
Number of pages9
JournalGut Microbes
Volume4
Issue number6
DOIs
StatePublished - 2013

Fingerprint

Helicobacter pylori
Stomach Neoplasms
Biomarkers
Tumor Biomarkers
Developing Countries
Anti-Bacterial Agents
Morbidity
Mortality
Population

ASJC Scopus subject areas

  • Gastroenterology
  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology

Cite this

Biomarkers of Helicobacter pylori-associated gastric cancer. / Cooke, Cara L.; Torres, Javier; Solnick, Jay V.

In: Gut Microbes, Vol. 4, No. 6, 2013, p. 532-540.

Research output: Contribution to journalArticle

Cooke, Cara L. ; Torres, Javier ; Solnick, Jay V. / Biomarkers of Helicobacter pylori-associated gastric cancer. In: Gut Microbes. 2013 ; Vol. 4, No. 6. pp. 532-540.
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