@inproceedings{c32b06f1200241d2ae5d7f6704022ce2,
title = "Biology of retinoschisin",
abstract = "There is good evidence that retinoschisin (RS1) is one of the key participants in retinal cell adhesion processes controlling the formation of retinal cell layers and mosaics. Loss-of-function mutations in the X-linked retinoschisis (RS1) gene lead to splitting within the retina, a condition known as the X-linked juvenile retinoschisis (XLRS). XLRS causes impairment of visual activity in young males and frequently progresses to even more severe reduction of both central and peripheral vision with age. This perspective reviews progress in the field of RS1 biology and pathophysiology.",
keywords = "Bipolar Cells, Discoidin Domain, Gene Therapy, Mutations, Photoreceptors, Retina, Retinoschisin, Synapse, X-Linked Retinoschisis",
author = "Camasamudram Vijayasarathy and Lucia Ziccardi and Sieving, {Paul A.}",
year = "2012",
doi = "10.1007/978-1-4614-0631-0_64",
language = "English (US)",
isbn = "9781461406303",
series = "Advances in Experimental Medicine and Biology",
pages = "513--518",
editor = "Matthew LaVail and Robert Anderson and Christian Grimm and John Ash and Joe Hollyfield",
booktitle = "Retinal Degenerative Diseases",
}