Biological NMR spectral analysis by an expert system

John L. Chow, Karl N. Levitt, Gerald J Kost

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

An expert system has been developed to facilitate biological 31-phosphorus nuclear magnetic resonance (31-PNMR) spectral analysis and interpretation. The expert system represents knowledge as production rules that reason about signal extraction, noise treatment, resonance assignment, intracellular pH determination, and metabolite intensity quantitation. The results from analysis of NMR spectra obtained from cardiovascular studies demonstrated that this artificial intelligence technique combined with statistical and numerical methods provides a framework for an efficient and reliable system for the analysis of complex, noisy biological 31-PNMR spectra.

Original languageEnglish (US)
Title of host publicationIEEE/Engineering in Medicine and Biology Society Annual Conference
Place of PublicationPiscataway, NJ, United States
PublisherPubl by IEEE
Pages1391-1392
Number of pages2
Volume10 pt 3
StatePublished - 1988
EventProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA
Duration: Nov 4 1988Nov 7 1988

Other

OtherProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityNew Orleans, LA, USA
Period11/4/8811/7/88

Fingerprint

Spectrum analysis
Expert systems
Nuclear magnetic resonance
Phosphorus
Metabolites
Artificial intelligence
Numerical methods
Statistical methods

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Chow, J. L., Levitt, K. N., & Kost, G. J. (1988). Biological NMR spectral analysis by an expert system. In IEEE/Engineering in Medicine and Biology Society Annual Conference (Vol. 10 pt 3, pp. 1391-1392). Piscataway, NJ, United States: Publ by IEEE.

Biological NMR spectral analysis by an expert system. / Chow, John L.; Levitt, Karl N.; Kost, Gerald J.

IEEE/Engineering in Medicine and Biology Society Annual Conference. Vol. 10 pt 3 Piscataway, NJ, United States : Publ by IEEE, 1988. p. 1391-1392.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chow, JL, Levitt, KN & Kost, GJ 1988, Biological NMR spectral analysis by an expert system. in IEEE/Engineering in Medicine and Biology Society Annual Conference. vol. 10 pt 3, Publ by IEEE, Piscataway, NJ, United States, pp. 1391-1392, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, 11/4/88.
Chow JL, Levitt KN, Kost GJ. Biological NMR spectral analysis by an expert system. In IEEE/Engineering in Medicine and Biology Society Annual Conference. Vol. 10 pt 3. Piscataway, NJ, United States: Publ by IEEE. 1988. p. 1391-1392
Chow, John L. ; Levitt, Karl N. ; Kost, Gerald J. / Biological NMR spectral analysis by an expert system. IEEE/Engineering in Medicine and Biology Society Annual Conference. Vol. 10 pt 3 Piscataway, NJ, United States : Publ by IEEE, 1988. pp. 1391-1392
@inproceedings{e154503d39b8451593fca4c09b39ede7,
title = "Biological NMR spectral analysis by an expert system",
abstract = "An expert system has been developed to facilitate biological 31-phosphorus nuclear magnetic resonance (31-PNMR) spectral analysis and interpretation. The expert system represents knowledge as production rules that reason about signal extraction, noise treatment, resonance assignment, intracellular pH determination, and metabolite intensity quantitation. The results from analysis of NMR spectra obtained from cardiovascular studies demonstrated that this artificial intelligence technique combined with statistical and numerical methods provides a framework for an efficient and reliable system for the analysis of complex, noisy biological 31-PNMR spectra.",
author = "Chow, {John L.} and Levitt, {Karl N.} and Kost, {Gerald J}",
year = "1988",
language = "English (US)",
volume = "10 pt 3",
pages = "1391--1392",
booktitle = "IEEE/Engineering in Medicine and Biology Society Annual Conference",
publisher = "Publ by IEEE",

}

TY - GEN

T1 - Biological NMR spectral analysis by an expert system

AU - Chow, John L.

AU - Levitt, Karl N.

AU - Kost, Gerald J

PY - 1988

Y1 - 1988

N2 - An expert system has been developed to facilitate biological 31-phosphorus nuclear magnetic resonance (31-PNMR) spectral analysis and interpretation. The expert system represents knowledge as production rules that reason about signal extraction, noise treatment, resonance assignment, intracellular pH determination, and metabolite intensity quantitation. The results from analysis of NMR spectra obtained from cardiovascular studies demonstrated that this artificial intelligence technique combined with statistical and numerical methods provides a framework for an efficient and reliable system for the analysis of complex, noisy biological 31-PNMR spectra.

AB - An expert system has been developed to facilitate biological 31-phosphorus nuclear magnetic resonance (31-PNMR) spectral analysis and interpretation. The expert system represents knowledge as production rules that reason about signal extraction, noise treatment, resonance assignment, intracellular pH determination, and metabolite intensity quantitation. The results from analysis of NMR spectra obtained from cardiovascular studies demonstrated that this artificial intelligence technique combined with statistical and numerical methods provides a framework for an efficient and reliable system for the analysis of complex, noisy biological 31-PNMR spectra.

UR - http://www.scopus.com/inward/record.url?scp=0024168557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024168557&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0024168557

VL - 10 pt 3

SP - 1391

EP - 1392

BT - IEEE/Engineering in Medicine and Biology Society Annual Conference

PB - Publ by IEEE

CY - Piscataway, NJ, United States

ER -