Biodegradable PLA-PGA polymers for tissue engineering in orthopaedics

C. M. Agrawal, K. A. Athanasiou, J. D. Heckman

Research output: Contribution to journalArticle

91 Scopus citations

Abstract

Polymers belonging to the family of polylactic acid (PLA) and polyglycolic acid (PGA) play an important role in the field of tissue engineering related to orthopaedics. These polymers degrade by hydrolysis and have a range of mechanical and physical properties. Their degradation characteristics depend on several parameters including their molecular structure, crystallinity, and copolymer ratio. Such polymers can be fashioned into porous scaffolds using a variety of techniques which have been described in this review paper. Although their future appears to be bright, several questions regarding the biocompatibility of these materials linger and have to be answered before their wide scale use.

Original languageEnglish (US)
Pages (from-to)115-128
Number of pages14
JournalMaterials Science Forum
Volume250
StatePublished - 1997
Externally publishedYes

Keywords

  • Degradation
  • Fabrication
  • Polyglycolic Acid
  • Polylactic Acid
  • Porous
  • Scaffolds

ASJC Scopus subject areas

  • Materials Science(all)

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  • Cite this

    Agrawal, C. M., Athanasiou, K. A., & Heckman, J. D. (1997). Biodegradable PLA-PGA polymers for tissue engineering in orthopaedics. Materials Science Forum, 250, 115-128.