Abstract
Tissue engineering can be a boon in treating lesions of the disc in the temporomandibular joint (TMJ). Unfortunately, little is known about its biochemical content, so we analysed the discs of six slaughtered pigs. We measured the content and distribution of total DNA, glycosaminoglycan, and collagen. The mean (S.D.) content of DNA was 0.14% (0.08%) of the dry weight, of glycosaminoglycan 0.96% (0.39%), and of collagen 68.2% (14.5%). There were no significant differences from top to bottom, but from front to back the smallest concentration of glycosaminoglycan was in the posterior band, and the highest concentration of collagen was in the intermediate zone. The concentrations of DNA and glycosaminoglycan were higher in the medial than in the lateral area of the disc.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 124-128 |
| Number of pages | 5 |
| Journal | British Journal of Oral and Maxillofacial Surgery |
| Volume | 44 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 2006 |
| Externally published | Yes |
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Keywords
- Collagen
- DNA
- Glycosaminoglycan
- Porcine
- TMJ disc
ASJC Scopus subject areas
- Dentistry(all)
- Otorhinolaryngology
- Surgery
Cite this
Biochemical analysis of the porcine temporomandibular joint disc. / Almarza, A. J.; Bean, A. C.; Baggett, L. S.; Athanasiou, K. A.
In: British Journal of Oral and Maxillofacial Surgery, Vol. 44, No. 2, 04.2006, p. 124-128.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biochemical analysis of the porcine temporomandibular joint disc
AU - Almarza, A. J.
AU - Bean, A. C.
AU - Baggett, L. S.
AU - Athanasiou, K. A.
PY - 2006/4
Y1 - 2006/4
N2 - Tissue engineering can be a boon in treating lesions of the disc in the temporomandibular joint (TMJ). Unfortunately, little is known about its biochemical content, so we analysed the discs of six slaughtered pigs. We measured the content and distribution of total DNA, glycosaminoglycan, and collagen. The mean (S.D.) content of DNA was 0.14% (0.08%) of the dry weight, of glycosaminoglycan 0.96% (0.39%), and of collagen 68.2% (14.5%). There were no significant differences from top to bottom, but from front to back the smallest concentration of glycosaminoglycan was in the posterior band, and the highest concentration of collagen was in the intermediate zone. The concentrations of DNA and glycosaminoglycan were higher in the medial than in the lateral area of the disc.
AB - Tissue engineering can be a boon in treating lesions of the disc in the temporomandibular joint (TMJ). Unfortunately, little is known about its biochemical content, so we analysed the discs of six slaughtered pigs. We measured the content and distribution of total DNA, glycosaminoglycan, and collagen. The mean (S.D.) content of DNA was 0.14% (0.08%) of the dry weight, of glycosaminoglycan 0.96% (0.39%), and of collagen 68.2% (14.5%). There were no significant differences from top to bottom, but from front to back the smallest concentration of glycosaminoglycan was in the posterior band, and the highest concentration of collagen was in the intermediate zone. The concentrations of DNA and glycosaminoglycan were higher in the medial than in the lateral area of the disc.
KW - Collagen
KW - DNA
KW - Glycosaminoglycan
KW - Porcine
KW - TMJ disc
UR - http://www.scopus.com/inward/record.url?scp=33644655693&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33644655693&partnerID=8YFLogxK
U2 - 10.1016/j.bjoms.2005.05.002
DO - 10.1016/j.bjoms.2005.05.002
M3 - Article
VL - 44
SP - 124
EP - 128
JO - British Journal of Oral and Maxillofacial Surgery
JF - British Journal of Oral and Maxillofacial Surgery
SN - 0266-4356
IS - 2
ER -