Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage

Ana M. Avalos Mishaan, Nelly Zavaleta, Ian J. Griffin, David C. Hilmers, Keli M. Hawthorne, Steven A. Abrams

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective To test the hypothesis that micronutrient beverages can provide the daily iron and zinc needs of small children. Study design Forty children aged 6 to 9 years were recruited (Lima, Peru). For 4 weeks, they received a daily serving of a beverage containing multiple micronutrients. Over 2 consecutive days, subjects received stable isotope-labeled servings of the beverage with and without a meal as well as an intravenous dose of zinc. Iron and zinc bioavailability were assessed using mass spectrometry. Results Iron absorption was significantly lower with a meal than without (9.8 ± 6.7% versus 11.6 ± 6.9%, P=.04), but zinc absorption was not (24.5 ± 10.7% versus 22.8 ± 7.6%, P=.2). In either case, however, a single daily serving provided most of the iron and zinc requirements for the children. Conclusions Single daily servings of multinutrient-fortified beverages can meet much of the mineral needs for small children. Food has a small inhibitory effect on iron, but not zinc, absorption; therefore, these beverages can be efficacious even when given with a meal.

Original languageEnglish (US)
Pages (from-to)26-31
Number of pages6
JournalJournal of Pediatrics
Volume145
Issue number1
DOIs
StatePublished - Jul 2004
Externally publishedYes

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Micronutrients
Beverages
Biological Availability
Zinc
Iron
Meals
Peru
Isotopes
Minerals
Mass Spectrometry
Food

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Avalos Mishaan, A. M., Zavaleta, N., Griffin, I. J., Hilmers, D. C., Hawthorne, K. M., & Abrams, S. A. (2004). Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage. Journal of Pediatrics, 145(1), 26-31. https://doi.org/10.1016/j.jpeds.2004.02.031

Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage. / Avalos Mishaan, Ana M.; Zavaleta, Nelly; Griffin, Ian J.; Hilmers, David C.; Hawthorne, Keli M.; Abrams, Steven A.

In: Journal of Pediatrics, Vol. 145, No. 1, 07.2004, p. 26-31.

Research output: Contribution to journalArticle

Avalos Mishaan, AM, Zavaleta, N, Griffin, IJ, Hilmers, DC, Hawthorne, KM & Abrams, SA 2004, 'Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage', Journal of Pediatrics, vol. 145, no. 1, pp. 26-31. https://doi.org/10.1016/j.jpeds.2004.02.031
Avalos Mishaan AM, Zavaleta N, Griffin IJ, Hilmers DC, Hawthorne KM, Abrams SA. Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage. Journal of Pediatrics. 2004 Jul;145(1):26-31. https://doi.org/10.1016/j.jpeds.2004.02.031
Avalos Mishaan, Ana M. ; Zavaleta, Nelly ; Griffin, Ian J. ; Hilmers, David C. ; Hawthorne, Keli M. ; Abrams, Steven A. / Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage. In: Journal of Pediatrics. 2004 ; Vol. 145, No. 1. pp. 26-31.
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