Abstract
During the last larval stadium of the cabbage looper, Trichoplusia ni, Hubner, the prepupal burst of juvenile hormone (JH) stimulates the appearance of juvenile hormone esterase (JHE) which, in turn, degrades the JH. Disruption of this prepupal burst of JH by anti-juvenile hormones (AJHs) such as fluoromevalonolactone, result in a variety of teratogenic effects including delayed tanning and/or pupation, malformed larvae and reduced JHE activity. Although general toxicants and esterase inhibitors may also cause malformed larvae, there is usually no delay in tanning and/or pupation. These observations provide the basis for a simple, rapid AJH bioassay using an economically important pest insect (T. ni). A simple 'key' was devised to help facilitate the use of this bioassay.
| Original language | English (US) |
|---|---|
| Title of host publication | ACS Symposium Series |
| Place of Publication | Washington, DC, USA |
| Publisher | ACS |
| Pages | 293-306 |
| Number of pages | 14 |
| ISBN (Print) | 0841209103 |
| State | Published - 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Chemistry(all)
Cite this
BIOASSAY OF ANTI JUVENILE HORMONE COMPOUNDS : AN ALTERNATIVE APPROACH. / Sparks, Thomas C.; Roe, R. Michael; Buehler, Adrian; Hammock, Bruce D.
ACS Symposium Series. Washington, DC, USA : ACS, 1985. p. 293-306.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - BIOASSAY OF ANTI JUVENILE HORMONE COMPOUNDS
T2 - AN ALTERNATIVE APPROACH.
AU - Sparks, Thomas C.
AU - Roe, R. Michael
AU - Buehler, Adrian
AU - Hammock, Bruce D.
PY - 1985
Y1 - 1985
N2 - During the last larval stadium of the cabbage looper, Trichoplusia ni, Hubner, the prepupal burst of juvenile hormone (JH) stimulates the appearance of juvenile hormone esterase (JHE) which, in turn, degrades the JH. Disruption of this prepupal burst of JH by anti-juvenile hormones (AJHs) such as fluoromevalonolactone, result in a variety of teratogenic effects including delayed tanning and/or pupation, malformed larvae and reduced JHE activity. Although general toxicants and esterase inhibitors may also cause malformed larvae, there is usually no delay in tanning and/or pupation. These observations provide the basis for a simple, rapid AJH bioassay using an economically important pest insect (T. ni). A simple 'key' was devised to help facilitate the use of this bioassay.
AB - During the last larval stadium of the cabbage looper, Trichoplusia ni, Hubner, the prepupal burst of juvenile hormone (JH) stimulates the appearance of juvenile hormone esterase (JHE) which, in turn, degrades the JH. Disruption of this prepupal burst of JH by anti-juvenile hormones (AJHs) such as fluoromevalonolactone, result in a variety of teratogenic effects including delayed tanning and/or pupation, malformed larvae and reduced JHE activity. Although general toxicants and esterase inhibitors may also cause malformed larvae, there is usually no delay in tanning and/or pupation. These observations provide the basis for a simple, rapid AJH bioassay using an economically important pest insect (T. ni). A simple 'key' was devised to help facilitate the use of this bioassay.
UR - http://www.scopus.com/inward/record.url?scp=0021838538&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021838538&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0021838538
SN - 0841209103
SP - 293
EP - 306
BT - ACS Symposium Series
PB - ACS
CY - Washington, DC, USA
ER -