Beyond counting photons

Trials and trends in vertebrate visual transduction

Marie E Burns, Vadim Y. Arshavsky

Research output: Contribution to journalArticle

169 Citations (Scopus)

Abstract

For over 30 years, photoreceptors have been an outstanding model system for elucidating basic principles in sensory transduction and G protein signaling. Recently, photoreceptors have become an equally attractive model for studying many facets of neuronal cell biology. The primary goal of this review is to illustrate this rapidly growing trend. We will highlight the areas of active research in photoreceptor biology that reveal how different specialized compartments of the cell cooperate in fulfilling its overall function: converting photon absorption into changes in neurotransmitter release. The same trend brings us closer to understanding how defects in photoreceptor signaling can lead to cell death and retinal degeneration.

Original languageEnglish (US)
Pages (from-to)387-401
Number of pages15
JournalNeuron
Volume48
Issue number3
DOIs
StatePublished - Nov 3 2005

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Retinal Degeneration
Photons
GTP-Binding Proteins
Neurotransmitter Agents
Cell Biology
Vertebrates
Cell Death
Research

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Beyond counting photons : Trials and trends in vertebrate visual transduction. / Burns, Marie E; Arshavsky, Vadim Y.

In: Neuron, Vol. 48, No. 3, 03.11.2005, p. 387-401.

Research output: Contribution to journalArticle

Burns, Marie E ; Arshavsky, Vadim Y. / Beyond counting photons : Trials and trends in vertebrate visual transduction. In: Neuron. 2005 ; Vol. 48, No. 3. pp. 387-401.
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