Bending membranes on demand: Fluid phospholipid bilayers on topographically deformable substrates

Babak Sanii, Andreia Michelle Smith, Ravichandra Butti, Adrian M. Brozell, Atul N. Parikh

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

We combine hierarchical surface wrinkling of elastomers with lipid membrane deposition techniques to dynamically template complex three-dimensional topographies onto supported lipid bilayers. The real-time introduction of corresponding nano- to micrometer scale curvatures triggers spatially periodic, elastic bending of the bilayer, accompanied by molecular-level reorganizations. This ability to dynamically impose curvatures on supported bilayers and the ensuing re-equilibration promises fundamental material and biophysical investigations of curvature-dependent, static heterogeneities and dynamic reorganizations pervasive in biological membranes.

Original languageEnglish (US)
Pages (from-to)866-871
Number of pages6
JournalNano Letters
Volume8
Issue number3
DOIs
StatePublished - Mar 2008

Fingerprint

Elastomers
Biological membranes
Lipid bilayers
Phospholipids
Membrane Lipids
Topography
curvature
membranes
Membranes
Fluids
lipids
fluids
Substrates
elastic bending
wrinkling
elastomers
micrometers
topography
templates
actuators

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanical Engineering
  • Electronic, Optical and Magnetic Materials
  • Chemistry (miscellaneous)

Cite this

Sanii, B., Smith, A. M., Butti, R., Brozell, A. M., & Parikh, A. N. (2008). Bending membranes on demand: Fluid phospholipid bilayers on topographically deformable substrates. Nano Letters, 8(3), 866-871. https://doi.org/10.1021/nl073085b

Bending membranes on demand : Fluid phospholipid bilayers on topographically deformable substrates. / Sanii, Babak; Smith, Andreia Michelle; Butti, Ravichandra; Brozell, Adrian M.; Parikh, Atul N.

In: Nano Letters, Vol. 8, No. 3, 03.2008, p. 866-871.

Research output: Contribution to journalArticle

Sanii, B, Smith, AM, Butti, R, Brozell, AM & Parikh, AN 2008, 'Bending membranes on demand: Fluid phospholipid bilayers on topographically deformable substrates', Nano Letters, vol. 8, no. 3, pp. 866-871. https://doi.org/10.1021/nl073085b
Sanii, Babak ; Smith, Andreia Michelle ; Butti, Ravichandra ; Brozell, Adrian M. ; Parikh, Atul N. / Bending membranes on demand : Fluid phospholipid bilayers on topographically deformable substrates. In: Nano Letters. 2008 ; Vol. 8, No. 3. pp. 866-871.
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