Behavioral tests in monkey infants exposed embryonically to an oral contraceptive

M. S. Golub, L. Hayes, S. Prahalada, Andrew G Hendrickx

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The behavior of rhesus monkey infants exposed to high levels (20 to 100 x the human therapeutic dosage) of an estrogen-progesterone contraceptive (Norlestrin) during embryogenesis was compared to that of untreated controls. No serious deficiencies in regulation of activity, motor maturity, manual dexterity or discrimination learning were recorded in the 3 to 5month old infants. In addition, age appropriate sex-differentiated behavior was observed in social groups of treated infants at 5 and 11 months of age. On the basis of this information it seems unlikely that accidental use 5 month birth control pills during early pregnancy will seriously affect behavioral competence of offspring during infancy.

Original languageEnglish (US)
Pages (from-to)301-304
Number of pages4
JournalNeurobehavioral Toxicology and Teratology
Issue number3
StatePublished - 1983

ASJC Scopus subject areas

  • Embryology
  • Toxicology
  • Neuropsychology and Physiological Psychology


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