Behavioral tests in monkey infants exposed embryonically to an oral contraceptive

M. S. Golub, L. Hayes, S. Prahalada, Andrew G Hendrickx

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The behavior of rhesus monkey infants exposed to high levels (20 to 100 x the human therapeutic dosage) of an estrogen-progesterone contraceptive (Norlestrin) during embryogenesis was compared to that of untreated controls. No serious deficiencies in regulation of activity, motor maturity, manual dexterity or discrimination learning were recorded in the 3 to 5month old infants. In addition, age appropriate sex-differentiated behavior was observed in social groups of treated infants at 5 and 11 months of age. On the basis of this information it seems unlikely that accidental use 5 month birth control pills during early pregnancy will seriously affect behavioral competence of offspring during infancy.

Original languageEnglish (US)
Pages (from-to)301-304
Number of pages4
JournalNeurobehavioral Toxicology and Teratology
Volume5
Issue number3
StatePublished - 1983

Fingerprint

Oral Contraceptives
Haplorhini
Contraceptive Agents
Progesterone
Discrimination Learning
Estrogens
Macaca mulatta
Contraception
Sexual Behavior
Mental Competency
Embryonic Development
Motor Activity
Pregnancy
Behavior Rating Scale
Therapeutics
norlestrin

ASJC Scopus subject areas

  • Embryology
  • Toxicology
  • Neuropsychology and Physiological Psychology

Cite this

Golub, M. S., Hayes, L., Prahalada, S., & Hendrickx, A. G. (1983). Behavioral tests in monkey infants exposed embryonically to an oral contraceptive. Neurobehavioral Toxicology and Teratology, 5(3), 301-304.

Behavioral tests in monkey infants exposed embryonically to an oral contraceptive. / Golub, M. S.; Hayes, L.; Prahalada, S.; Hendrickx, Andrew G.

In: Neurobehavioral Toxicology and Teratology, Vol. 5, No. 3, 1983, p. 301-304.

Research output: Contribution to journalArticle

Golub, MS, Hayes, L, Prahalada, S & Hendrickx, AG 1983, 'Behavioral tests in monkey infants exposed embryonically to an oral contraceptive', Neurobehavioral Toxicology and Teratology, vol. 5, no. 3, pp. 301-304.
Golub, M. S. ; Hayes, L. ; Prahalada, S. ; Hendrickx, Andrew G. / Behavioral tests in monkey infants exposed embryonically to an oral contraceptive. In: Neurobehavioral Toxicology and Teratology. 1983 ; Vol. 5, No. 3. pp. 301-304.
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