Abstract
Background. The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass (CPB) are reviewed. Methods. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and retinal angiography, and imaging-based evidence for postoperative cerebral edema, are discussed. Preliminary results from a prospective clinical trial assessing cognitive dysfunction after beating heart versus conventional coronary artery bypass with CPB are discussed. Results. Initial evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented. Conclusions. Beating heart surgery results in less potential for generation of cerebral emboli and appears to produce a lower incidence of cognitive dysfunction in both short- and intermediate-term postoperative follow-up periods as compared with conventional coronary artery bypass surgery using CPB.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1498-1501 |
| Number of pages | 4 |
| Journal | Annals of Thoracic Surgery |
| Volume | 68 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
Beating heart surgery : Why expect less central nervous system morbidity? / Murkin, John M.; Boyd, Walter D; Ganapathy, Sugantha; Adams, Sandra J.; Peterson, Rhonda C.
In: Annals of Thoracic Surgery, Vol. 68, No. 4, 10.1999, p. 1498-1501.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Beating heart surgery
T2 - Why expect less central nervous system morbidity?
AU - Murkin, John M.
AU - Boyd, Walter D
AU - Ganapathy, Sugantha
AU - Adams, Sandra J.
AU - Peterson, Rhonda C.
PY - 1999/10
Y1 - 1999/10
N2 - Background. The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass (CPB) are reviewed. Methods. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and retinal angiography, and imaging-based evidence for postoperative cerebral edema, are discussed. Preliminary results from a prospective clinical trial assessing cognitive dysfunction after beating heart versus conventional coronary artery bypass with CPB are discussed. Results. Initial evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented. Conclusions. Beating heart surgery results in less potential for generation of cerebral emboli and appears to produce a lower incidence of cognitive dysfunction in both short- and intermediate-term postoperative follow-up periods as compared with conventional coronary artery bypass surgery using CPB.
AB - Background. The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass (CPB) are reviewed. Methods. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and retinal angiography, and imaging-based evidence for postoperative cerebral edema, are discussed. Preliminary results from a prospective clinical trial assessing cognitive dysfunction after beating heart versus conventional coronary artery bypass with CPB are discussed. Results. Initial evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented. Conclusions. Beating heart surgery results in less potential for generation of cerebral emboli and appears to produce a lower incidence of cognitive dysfunction in both short- and intermediate-term postoperative follow-up periods as compared with conventional coronary artery bypass surgery using CPB.
UR - http://www.scopus.com/inward/record.url?scp=0032721086&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032721086&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(99)00953-4
DO - 10.1016/S0003-4975(99)00953-4
M3 - Article
C2 - 10543553
AN - SCOPUS:0032721086
VL - 68
SP - 1498
EP - 1501
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 4
ER -