Bartonella infection in hematophagous, insectivorous, and phytophagous bat populations of Central Mexico and the Yucatan Peninsula

Matthew J. Stuckey, Bruno B Chomel, Guillermo Galvez-Romero, José Ignacio Olave-Leyva, Cirani Obregón-Morales, Hayde Moreno-Sandoval, Nidia Aréchiga-Ceballos, Mónica Salas-Rojas, Alvaro Aguilar-Setién

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Although emerging nonviral pathogens remain relatively understudied in bat populations, there is an increasing focus on identifying bat-associated bartonellae around the world. Many novel Bartonella strains have been described from both bats and their arthropod ectoparasites, including Bartonella mayotimonensis, a zoonotic agent of human endocarditis. This cross-sectional study was designed to describe novel Bartonella strains isolated from bats sampled in Mexico and evaluate factors potentially associated with infection. A total of 238 bats belonging to seven genera were captured in five states of Central Mexico and the Yucatan Peninsula. Animals were screened by bacterial culture from whole blood and/or polymerase chain reaction of DNA extracted from heart tissue or blood. Bartonella spp. were isolated or detected in 54 (22.7%) bats, consisting of 41 (38%) hematophagous, 10 (16.4%) insectivorous, and three (4.3%) phytophagous individuals. This study also identified Balantiopteryx plicata as another possible bat reservoir of Bartonella. Univariate and multivariate logistic regression models suggested that Bartonella infection was positively associated with blood-feeding diet and ectoparasite burden. Phylogenetic analysis identified a number of genetic variants across hematophagous, phytophagous, and insectivorous bats that are unique from described bat-borne Bartonella species. However, these strains were closely related to those bartonellae previously identified in bat species from Latin America.

Original languageEnglish (US)
Pages (from-to)413-422
Number of pages10
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume97
Issue number2
DOIs
StatePublished - 2017

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ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Stuckey, M. J., Chomel, B. B., Galvez-Romero, G., Olave-Leyva, J. I., Obregón-Morales, C., Moreno-Sandoval, H., Aréchiga-Ceballos, N., Salas-Rojas, M., & Aguilar-Setién, A. (2017). Bartonella infection in hematophagous, insectivorous, and phytophagous bat populations of Central Mexico and the Yucatan Peninsula. American Journal of Tropical Medicine and Hygiene, 97(2), 413-422. https://doi.org/10.4269/ajtmh.16-0680