Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from the Philippines

Bruno B Chomel, Enrique T. Carlos, Rickie W. Kasten, Kazuhiro Yamamoto, Chao Chin Chang, Rodhora S. Carlos, Marie V. Abenes, Caroline M. Pajares

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Abstract

One hundred seven domestic cats from The Philippines were serologically tested to establish the prevalence of Bartonella infection. A subset of 31 of these cats also had whole blood collected to tentatively isolate Bartonella strains. Bartonella henselae and B. clarridgeiae were isolated from 19 (61%) of these cats. Bartonella henselae type I was isolated from 17 (89%) of the 19 culture-positive cats. Six cats (31%) were infected with B. clarridgeiae, of which four were coinfected with B. henselae. Sixty-eight percent (73 of 107) and 65% (70 of 107) of the cats had antibodies to B. henselae and B. clarridgeiae, respectively, detected by an immunofluorescence antibody (IFA) test at a titer ≥ 1:64. When tested by enzyme immunoassay (EIA), 67 cats (62.6%) had antibodies to B. henselae and 71 cats (66.4%) had antibodies to B. clarridgeiae. Compared with the IFA test, the B. henselae EIA had a sensitivity of 90.4% and a specificity of 97%, with positive and negative predictive values of 98.5% and 82.5%, respectively. Similarly, the B. clarridgeiae EIA had a sensitivity of 97% and a specificity of 92% specificity, with positive and negative predictive values of 95.8% and 94.4%, respectively. The presence of antibodies to Bartonella was strongly associated with flea infestation. Domestic cats represent a large reservoir of Bartonella infection in the Philippines.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume60
Issue number4
StatePublished - Apr 1999

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ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Chomel, B. B., Carlos, E. T., Kasten, R. W., Yamamoto, K., Chang, C. C., Carlos, R. S., Abenes, M. V., & Pajares, C. M. (1999). Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from the Philippines. American Journal of Tropical Medicine and Hygiene, 60(4), 593-597.