Axonal transport of proteins in experimental neuropathies

David E Pleasure, Kathleen G. Mishler, W. King Engel

Research output: Contribution to journalArticle

83 Scopus citations

Abstract

Axoplasmic flow of proteins is interrupted in cats with neuropathy induced by acrylamide, but it is not interrupted in normal cats and in those with neuropathy induced by tri-orthocresyl phosphate. The proteins move from lumbosacral motor neurons along the ventral roots and from ganglion cells toward the spinal cord along the dorsal roots at about 11/2 millimeters per day.

Original languageEnglish (US)
Pages (from-to)524-525
Number of pages2
JournalScience
Volume166
Issue number3904
StatePublished - 1969
Externally publishedYes

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    Pleasure, D. E., Mishler, K. G., & Engel, W. K. (1969). Axonal transport of proteins in experimental neuropathies. Science, 166(3904), 524-525.