Autosomal-dominant polycystic kidney disease in a family of scottish fold cats

Kyoung Won Seo, Sae um Kim, Jin ok Ahn, Ye rin Coh, Sung young Han, Hwa young Youn

Research output: Contribution to journalArticle

Abstract

Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persian and Persian-related breeds, and is sporadically reported in Scottish Fold cats. A 5-year-old male Scottish Fold cat was diagnosed with polycystic kidney disease based on screening tests and abdominal ultrasonography and died 3.5 months after diagnosis. The cat had 14 kittens with three queens, including his female sibling, with an age range of 3 months to 8 years. Genetic testing to confirm the genetic transmission of AD-PKD which detects the mutated PKD1 gene was performed. Abdominal ultrasonography confirmed the presence of renal cysts. Nineteen cats were screened in the present study (13 males and 6 females), with an age range of 3 months to 8 years. The results of renal ultrasonography agreed with the genetic test results in the 19 cats in which both tests were performed and 8 cats were diagnosed as ADPKD based on these tests. AD-PKD has not been investigated in cats in South Korea. Moreover, this is the first report of AD-PKD in a family unit of Scottish Fold cats.

Original languageEnglish (US)
Pages (from-to)726-728
Number of pages3
JournalJournal of Veterinary Clinics
Volume27
Issue number6
StatePublished - Dec 1 2010
Externally publishedYes

Fingerprint

Autosomal Dominant Polycystic Kidney
Cats
cats
ultrasonography
Ultrasonography
testing
kidneys
Kidney
Polycystic Kidney Diseases
Republic of Korea
autosomal dominant polycystic kidney disease
kittens
Genetic Testing
South Korea
Cysts
screening
breeds

Keywords

  • Autosomal dominant polycystic kidney disease
  • Feline
  • PCR/RFLP
  • Scottish fold cats

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Seo, K. W., Kim, S. U., Ahn, J. O., Coh, Y. R., Han, S. Y., & Youn, H. Y. (2010). Autosomal-dominant polycystic kidney disease in a family of scottish fold cats. Journal of Veterinary Clinics, 27(6), 726-728.

Autosomal-dominant polycystic kidney disease in a family of scottish fold cats. / Seo, Kyoung Won; Kim, Sae um; Ahn, Jin ok; Coh, Ye rin; Han, Sung young; Youn, Hwa young.

In: Journal of Veterinary Clinics, Vol. 27, No. 6, 01.12.2010, p. 726-728.

Research output: Contribution to journalArticle

Seo, KW, Kim, SU, Ahn, JO, Coh, YR, Han, SY & Youn, HY 2010, 'Autosomal-dominant polycystic kidney disease in a family of scottish fold cats', Journal of Veterinary Clinics, vol. 27, no. 6, pp. 726-728.
Seo, Kyoung Won ; Kim, Sae um ; Ahn, Jin ok ; Coh, Ye rin ; Han, Sung young ; Youn, Hwa young. / Autosomal-dominant polycystic kidney disease in a family of scottish fold cats. In: Journal of Veterinary Clinics. 2010 ; Vol. 27, No. 6. pp. 726-728.
@article{34dbbcc7ea8445c8bae5b9ce5d432ea4,
title = "Autosomal-dominant polycystic kidney disease in a family of scottish fold cats",
abstract = "Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persian and Persian-related breeds, and is sporadically reported in Scottish Fold cats. A 5-year-old male Scottish Fold cat was diagnosed with polycystic kidney disease based on screening tests and abdominal ultrasonography and died 3.5 months after diagnosis. The cat had 14 kittens with three queens, including his female sibling, with an age range of 3 months to 8 years. Genetic testing to confirm the genetic transmission of AD-PKD which detects the mutated PKD1 gene was performed. Abdominal ultrasonography confirmed the presence of renal cysts. Nineteen cats were screened in the present study (13 males and 6 females), with an age range of 3 months to 8 years. The results of renal ultrasonography agreed with the genetic test results in the 19 cats in which both tests were performed and 8 cats were diagnosed as ADPKD based on these tests. AD-PKD has not been investigated in cats in South Korea. Moreover, this is the first report of AD-PKD in a family unit of Scottish Fold cats.",
keywords = "Autosomal dominant polycystic kidney disease, Feline, PCR/RFLP, Scottish fold cats",
author = "Seo, {Kyoung Won} and Kim, {Sae um} and Ahn, {Jin ok} and Coh, {Ye rin} and Han, {Sung young} and Youn, {Hwa young}",
year = "2010",
month = "12",
day = "1",
language = "English (US)",
volume = "27",
pages = "726--728",
journal = "Journal of Veterinary Clinics",
issn = "1598-298X",
publisher = "Korean Society of Veterinary Clinics",
number = "6",

}

TY - JOUR

T1 - Autosomal-dominant polycystic kidney disease in a family of scottish fold cats

AU - Seo, Kyoung Won

AU - Kim, Sae um

AU - Ahn, Jin ok

AU - Coh, Ye rin

AU - Han, Sung young

AU - Youn, Hwa young

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persian and Persian-related breeds, and is sporadically reported in Scottish Fold cats. A 5-year-old male Scottish Fold cat was diagnosed with polycystic kidney disease based on screening tests and abdominal ultrasonography and died 3.5 months after diagnosis. The cat had 14 kittens with three queens, including his female sibling, with an age range of 3 months to 8 years. Genetic testing to confirm the genetic transmission of AD-PKD which detects the mutated PKD1 gene was performed. Abdominal ultrasonography confirmed the presence of renal cysts. Nineteen cats were screened in the present study (13 males and 6 females), with an age range of 3 months to 8 years. The results of renal ultrasonography agreed with the genetic test results in the 19 cats in which both tests were performed and 8 cats were diagnosed as ADPKD based on these tests. AD-PKD has not been investigated in cats in South Korea. Moreover, this is the first report of AD-PKD in a family unit of Scottish Fold cats.

AB - Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persian and Persian-related breeds, and is sporadically reported in Scottish Fold cats. A 5-year-old male Scottish Fold cat was diagnosed with polycystic kidney disease based on screening tests and abdominal ultrasonography and died 3.5 months after diagnosis. The cat had 14 kittens with three queens, including his female sibling, with an age range of 3 months to 8 years. Genetic testing to confirm the genetic transmission of AD-PKD which detects the mutated PKD1 gene was performed. Abdominal ultrasonography confirmed the presence of renal cysts. Nineteen cats were screened in the present study (13 males and 6 females), with an age range of 3 months to 8 years. The results of renal ultrasonography agreed with the genetic test results in the 19 cats in which both tests were performed and 8 cats were diagnosed as ADPKD based on these tests. AD-PKD has not been investigated in cats in South Korea. Moreover, this is the first report of AD-PKD in a family unit of Scottish Fold cats.

KW - Autosomal dominant polycystic kidney disease

KW - Feline

KW - PCR/RFLP

KW - Scottish fold cats

UR - http://www.scopus.com/inward/record.url?scp=79958039847&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79958039847&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:79958039847

VL - 27

SP - 726

EP - 728

JO - Journal of Veterinary Clinics

JF - Journal of Veterinary Clinics

SN - 1598-298X

IS - 6

ER -