Autosomal-dominant polycystic kidney disease in a family of scottish fold cats

Kyoung Won Seo, Sae um Kim, Jin ok Ahn, Ye rin Coh, Sung young Han, Hwa young Youn

Research output: Contribution to journalArticlepeer-review


Autosomal-dominant polycystic kidney disease (AD-PKD) is common in Persian and Persian-related breeds, and is sporadically reported in Scottish Fold cats. A 5-year-old male Scottish Fold cat was diagnosed with polycystic kidney disease based on screening tests and abdominal ultrasonography and died 3.5 months after diagnosis. The cat had 14 kittens with three queens, including his female sibling, with an age range of 3 months to 8 years. Genetic testing to confirm the genetic transmission of AD-PKD which detects the mutated PKD1 gene was performed. Abdominal ultrasonography confirmed the presence of renal cysts. Nineteen cats were screened in the present study (13 males and 6 females), with an age range of 3 months to 8 years. The results of renal ultrasonography agreed with the genetic test results in the 19 cats in which both tests were performed and 8 cats were diagnosed as ADPKD based on these tests. AD-PKD has not been investigated in cats in South Korea. Moreover, this is the first report of AD-PKD in a family unit of Scottish Fold cats.

Original languageEnglish (US)
Pages (from-to)726-728
Number of pages3
JournalJournal of Veterinary Clinics
Issue number6
StatePublished - Dec 1 2010
Externally publishedYes


  • Autosomal dominant polycystic kidney disease
  • Feline
  • Scottish fold cats

ASJC Scopus subject areas

  • veterinary(all)


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