Abstract
The 2-deoxy-D-[14C]glucose (2-DG) autoradiographic method for determining regional brain glucose consumption has been applied successfully by a number of workers for mapping the alterations of brain glucose consumption which occur in association with experimental alterations of brain functional activity. This paper provides a framework for the interpretation of these and further studies by presenting: (1) the pattern of regional brain glucose consumption in the normal, resting, awake rat; (2) the anatomical identities of brain structures which on autoradiographs appear only as regional variations of optical density. For this purpose, a series of 2-DG autoradiographs of coronal brain sections from an injected animal is compared with adjacent labeled Nissl sections.
Original language | English (US) |
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Pages (from-to) | 335-359 |
Number of pages | 25 |
Journal | Journal of Comparative Neurology |
Volume | 177 |
Issue number | 2 |
State | Published - 1978 |
Externally published | Yes |
ASJC Scopus subject areas
- Neuroscience(all)