Abstract
The distribution of vitamin A in the kidney was investigated autoradi-ographically. Three hours after intravenous administration of [11, 12-3H]retinyl acetate to vitamin A-deficient rats, the vast majority of the label was present in cells of the proximal convoluted tubules. A very small number of endothelial cells in the medulla and interstitial cells in the cortex were also labeled. The evidence strongly suggests that the proximal convoluted tubule is the major renal site for vitamin A localization. The precise role the kidney plays in overall vitamin A metabolism remains uncertain.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 124-127 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 155 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1977 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Autoradiographic Localization of Vitamin A in the Kidney of Rats. / Plopper, Charles; Wallace, D. L.; Bucci, T. J.; Sauberlich, H. E.
In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 155, No. 1, 01.01.1977, p. 124-127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Autoradiographic Localization of Vitamin A in the Kidney of Rats
AU - Plopper, Charles
AU - Wallace, D. L.
AU - Bucci, T. J.
AU - Sauberlich, H. E.
PY - 1977/1/1
Y1 - 1977/1/1
N2 - The distribution of vitamin A in the kidney was investigated autoradi-ographically. Three hours after intravenous administration of [11, 12-3H]retinyl acetate to vitamin A-deficient rats, the vast majority of the label was present in cells of the proximal convoluted tubules. A very small number of endothelial cells in the medulla and interstitial cells in the cortex were also labeled. The evidence strongly suggests that the proximal convoluted tubule is the major renal site for vitamin A localization. The precise role the kidney plays in overall vitamin A metabolism remains uncertain.
AB - The distribution of vitamin A in the kidney was investigated autoradi-ographically. Three hours after intravenous administration of [11, 12-3H]retinyl acetate to vitamin A-deficient rats, the vast majority of the label was present in cells of the proximal convoluted tubules. A very small number of endothelial cells in the medulla and interstitial cells in the cortex were also labeled. The evidence strongly suggests that the proximal convoluted tubule is the major renal site for vitamin A localization. The precise role the kidney plays in overall vitamin A metabolism remains uncertain.
UR - http://www.scopus.com/inward/record.url?scp=0017646335&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017646335&partnerID=8YFLogxK
U2 - 10.3181/00379727-155-39758
DO - 10.3181/00379727-155-39758
M3 - Article
C2 - 859872
AN - SCOPUS:0017646335
VL - 155
SP - 124
EP - 127
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
SN - 1535-3702
IS - 1
ER -