Autoradiographic localization of vitamin A in the adrenal gland of rats

D. L. Wallace, Charles Plopper, T. J. Bucci, H. E. Sauberlich

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Cellular distribution of vitamin A in the rat adrenal was evaluated by autoradiography. Vitamin A was concentrated in the lipid droplets of epithelial cells of the zona fasciculata and zona reticularis. A small amount of vitamin A was also present in the cytoplasm and nucleus of these cells. The zona glomerulosa contained very little vitamin A either in lipid droplets or in the remainder of the cell. The medulla had essentially no vitamin A. Such strong cellular specificity for uptake of vitamin A by the cells of the zona fasciculata and zona reticularis supports the hypothesis that vitamin A is involved in synthesis of glucocorticoid hormones.

Original languageEnglish (US)
Pages (from-to)1693-1697
Number of pages5
JournalLife Sciences
Volume17
Issue number11
DOIs
StatePublished - Dec 1 1975
Externally publishedYes

Fingerprint

Adrenal Glands
Vitamin A
Rats
Zona Reticularis
Zona Fasciculata
Zona Glomerulosa
Lipids
Autoradiography
Cell Nucleus
Glucocorticoids
Cytoplasm
Epithelial Cells
Hormones

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Autoradiographic localization of vitamin A in the adrenal gland of rats. / Wallace, D. L.; Plopper, Charles; Bucci, T. J.; Sauberlich, H. E.

In: Life Sciences, Vol. 17, No. 11, 01.12.1975, p. 1693-1697.

Research output: Contribution to journalArticle

Wallace, D. L. ; Plopper, Charles ; Bucci, T. J. ; Sauberlich, H. E. / Autoradiographic localization of vitamin A in the adrenal gland of rats. In: Life Sciences. 1975 ; Vol. 17, No. 11. pp. 1693-1697.
@article{4609c93b85c74fe8a455a1e4642a9f38,
title = "Autoradiographic localization of vitamin A in the adrenal gland of rats",
abstract = "Cellular distribution of vitamin A in the rat adrenal was evaluated by autoradiography. Vitamin A was concentrated in the lipid droplets of epithelial cells of the zona fasciculata and zona reticularis. A small amount of vitamin A was also present in the cytoplasm and nucleus of these cells. The zona glomerulosa contained very little vitamin A either in lipid droplets or in the remainder of the cell. The medulla had essentially no vitamin A. Such strong cellular specificity for uptake of vitamin A by the cells of the zona fasciculata and zona reticularis supports the hypothesis that vitamin A is involved in synthesis of glucocorticoid hormones.",
author = "Wallace, {D. L.} and Charles Plopper and Bucci, {T. J.} and Sauberlich, {H. E.}",
year = "1975",
month = "12",
day = "1",
doi = "10.1016/0024-3205(75)90115-0",
language = "English (US)",
volume = "17",
pages = "1693--1697",
journal = "Life Sciences",
issn = "0024-3205",
publisher = "Elsevier Inc.",
number = "11",

}

TY - JOUR

T1 - Autoradiographic localization of vitamin A in the adrenal gland of rats

AU - Wallace, D. L.

AU - Plopper, Charles

AU - Bucci, T. J.

AU - Sauberlich, H. E.

PY - 1975/12/1

Y1 - 1975/12/1

N2 - Cellular distribution of vitamin A in the rat adrenal was evaluated by autoradiography. Vitamin A was concentrated in the lipid droplets of epithelial cells of the zona fasciculata and zona reticularis. A small amount of vitamin A was also present in the cytoplasm and nucleus of these cells. The zona glomerulosa contained very little vitamin A either in lipid droplets or in the remainder of the cell. The medulla had essentially no vitamin A. Such strong cellular specificity for uptake of vitamin A by the cells of the zona fasciculata and zona reticularis supports the hypothesis that vitamin A is involved in synthesis of glucocorticoid hormones.

AB - Cellular distribution of vitamin A in the rat adrenal was evaluated by autoradiography. Vitamin A was concentrated in the lipid droplets of epithelial cells of the zona fasciculata and zona reticularis. A small amount of vitamin A was also present in the cytoplasm and nucleus of these cells. The zona glomerulosa contained very little vitamin A either in lipid droplets or in the remainder of the cell. The medulla had essentially no vitamin A. Such strong cellular specificity for uptake of vitamin A by the cells of the zona fasciculata and zona reticularis supports the hypothesis that vitamin A is involved in synthesis of glucocorticoid hormones.

UR - http://www.scopus.com/inward/record.url?scp=0016789439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016789439&partnerID=8YFLogxK

U2 - 10.1016/0024-3205(75)90115-0

DO - 10.1016/0024-3205(75)90115-0

M3 - Article

C2 - 1207382

AN - SCOPUS:0016789439

VL - 17

SP - 1693

EP - 1697

JO - Life Sciences

JF - Life Sciences

SN - 0024-3205

IS - 11

ER -