Autoantibodies in Autism Spectrum Disorders (ASD)

Sharifia Wills, Maricel Cabanlit, Jeff Bennett, Paul Ashwood, David G Amaral, Judith A Van de Water

Research output: Chapter in Book/Report/Conference proceedingConference contribution

65 Citations (Scopus)

Abstract

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.

Original languageEnglish (US)
Title of host publicationAnnals of the New York Academy of Sciences
Pages79-91
Number of pages13
Volume1107
DOIs
StatePublished - Jun 2007

Publication series

NameAnnals of the New York Academy of Sciences
Volume1107
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Autoantibodies
Immune system
Antigens
Nonverbal Communication
Communication
Immune System
Autism Spectrum Disorder
Phenotype

Keywords

  • ASD
  • Autism
  • Autoantibodies
  • Brain
  • Immune system
  • Immunity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Wills, S., Cabanlit, M., Bennett, J., Ashwood, P., Amaral, D. G., & Van de Water, J. A. (2007). Autoantibodies in Autism Spectrum Disorders (ASD). In Annals of the New York Academy of Sciences (Vol. 1107, pp. 79-91). (Annals of the New York Academy of Sciences; Vol. 1107). https://doi.org/10.1196/annals.1381.009

Autoantibodies in Autism Spectrum Disorders (ASD). / Wills, Sharifia; Cabanlit, Maricel; Bennett, Jeff; Ashwood, Paul; Amaral, David G; Van de Water, Judith A.

Annals of the New York Academy of Sciences. Vol. 1107 2007. p. 79-91 (Annals of the New York Academy of Sciences; Vol. 1107).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wills, S, Cabanlit, M, Bennett, J, Ashwood, P, Amaral, DG & Van de Water, JA 2007, Autoantibodies in Autism Spectrum Disorders (ASD). in Annals of the New York Academy of Sciences. vol. 1107, Annals of the New York Academy of Sciences, vol. 1107, pp. 79-91. https://doi.org/10.1196/annals.1381.009
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water JA. Autoantibodies in Autism Spectrum Disorders (ASD). In Annals of the New York Academy of Sciences. Vol. 1107. 2007. p. 79-91. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1381.009
Wills, Sharifia ; Cabanlit, Maricel ; Bennett, Jeff ; Ashwood, Paul ; Amaral, David G ; Van de Water, Judith A. / Autoantibodies in Autism Spectrum Disorders (ASD). Annals of the New York Academy of Sciences. Vol. 1107 2007. pp. 79-91 (Annals of the New York Academy of Sciences).
@inproceedings{713cb904f2d54fe4bd38793c5910eadf,
title = "Autoantibodies in Autism Spectrum Disorders (ASD)",
abstract = "Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.",
keywords = "ASD, Autism, Autoantibodies, Brain, Immune system, Immunity",
author = "Sharifia Wills and Maricel Cabanlit and Jeff Bennett and Paul Ashwood and Amaral, {David G} and {Van de Water}, {Judith A}",
year = "2007",
month = "6",
doi = "10.1196/annals.1381.009",
language = "English (US)",
isbn = "1573316628",
volume = "1107",
series = "Annals of the New York Academy of Sciences",
pages = "79--91",
booktitle = "Annals of the New York Academy of Sciences",

}

TY - GEN

T1 - Autoantibodies in Autism Spectrum Disorders (ASD)

AU - Wills, Sharifia

AU - Cabanlit, Maricel

AU - Bennett, Jeff

AU - Ashwood, Paul

AU - Amaral, David G

AU - Van de Water, Judith A

PY - 2007/6

Y1 - 2007/6

N2 - Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.

AB - Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.

KW - ASD

KW - Autism

KW - Autoantibodies

KW - Brain

KW - Immune system

KW - Immunity

UR - http://www.scopus.com/inward/record.url?scp=34648820674&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34648820674&partnerID=8YFLogxK

U2 - 10.1196/annals.1381.009

DO - 10.1196/annals.1381.009

M3 - Conference contribution

C2 - 17804535

AN - SCOPUS:34648820674

SN - 1573316628

SN - 9781573316620

VL - 1107

T3 - Annals of the New York Academy of Sciences

SP - 79

EP - 91

BT - Annals of the New York Academy of Sciences

ER -