Abstract
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.
| Original language | English (US) |
|---|---|
| Title of host publication | Annals of the New York Academy of Sciences |
| Pages | 79-91 |
| Number of pages | 13 |
| Volume | 1107 |
| DOIs | |
| State | Published - Jun 2007 |
Publication series
| Name | Annals of the New York Academy of Sciences |
|---|---|
| Volume | 1107 |
| ISSN (Print) | 00778923 |
| ISSN (Electronic) | 17496632 |
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Keywords
- ASD
- Autism
- Autoantibodies
- Brain
- Immune system
- Immunity
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Autoantibodies in Autism Spectrum Disorders (ASD). / Wills, Sharifia; Cabanlit, Maricel; Bennett, Jeff; Ashwood, Paul; Amaral, David G; Van de Water, Judith A.
Annals of the New York Academy of Sciences. Vol. 1107 2007. p. 79-91 (Annals of the New York Academy of Sciences; Vol. 1107).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Autoantibodies in Autism Spectrum Disorders (ASD)
AU - Wills, Sharifia
AU - Cabanlit, Maricel
AU - Bennett, Jeff
AU - Ashwood, Paul
AU - Amaral, David G
AU - Van de Water, Judith A
PY - 2007/6
Y1 - 2007/6
N2 - Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.
AB - Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders defined behaviorally by abnormalities in social, verbal, and nonverbal communication. The etiologies of ASD are unknown, likely to be the result of a variety of numerous genetic, neurological, environmental, and immunological interactions that lead to a general behavioral phenotype defined as ASD. This review will focus on the various immune system anomalies, in particular, autoantibodies, which have been reported in subjects with ASD. In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD.
KW - ASD
KW - Autism
KW - Autoantibodies
KW - Brain
KW - Immune system
KW - Immunity
UR - http://www.scopus.com/inward/record.url?scp=34648820674&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34648820674&partnerID=8YFLogxK
U2 - 10.1196/annals.1381.009
DO - 10.1196/annals.1381.009
M3 - Conference contribution
C2 - 17804535
AN - SCOPUS:34648820674
SN - 1573316628
SN - 9781573316620
VL - 1107
T3 - Annals of the New York Academy of Sciences
SP - 79
EP - 91
BT - Annals of the New York Academy of Sciences
ER -