Autism in fragile X females

Randi J Hagerman; A. E. Chudley; J. H. Knoll; A. W. Jackson; M. Kemper; R. Ahmad

Autism in fragile X females

Randi J Hagerman, A. E. Chudley, J. H. Knoll, A. W. Jackson, M. Kemper, R. Ahmad

Research output: Contribution to journal › Article › peer-review

Abstract

We present two women with the fragile X syndrome (Martin-Bell syndrome) and autism. Both are mentally retarded, one mildly and one severely. Cytogenetic studies showed a high percentage of lymphocytes with the fragile X chromosome and inactivation occurring preferentially in the normal X chromosome. Autism is shown to be a severe behavioral and cognitive manifestation of the fragile X syndrome in females.

Original language	English (US)
Pages (from-to)	375-380
Number of pages	6
Journal	American Journal of Medical Genetics
Volume	23
Issue number	1-2
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Genetics(clinical)

Fingerprint Dive into the research topics of 'Autism in fragile X females'. Together they form a unique fingerprint.

Cite this

@article{389cc45dd0fb44c99dc127aff41a57eb,

title = "Autism in fragile X females",

abstract = "We present two women with the fragile X syndrome (Martin-Bell syndrome) and autism. Both are mentally retarded, one mildly and one severely. Cytogenetic studies showed a high percentage of lymphocytes with the fragile X chromosome and inactivation occurring preferentially in the normal X chromosome. Autism is shown to be a severe behavioral and cognitive manifestation of the fragile X syndrome in females.",

author = "Hagerman, {Randi J} and Chudley, {A. E.} and Knoll, {J. H.} and Jackson, {A. W.} and M. Kemper and R. Ahmad",

year = "1986",

language = "English (US)",

volume = "23",

pages = "375--380",

journal = "American Journal of Medical Genetics",

issn = "1552-4825",

publisher = "Wiley-Liss Inc.",

number = "1-2",

}

TY - JOUR

T1 - Autism in fragile X females

AU - Hagerman, Randi J

AU - Chudley, A. E.

AU - Knoll, J. H.

AU - Jackson, A. W.

AU - Kemper, M.

AU - Ahmad, R.

PY - 1986

Y1 - 1986

N2 - We present two women with the fragile X syndrome (Martin-Bell syndrome) and autism. Both are mentally retarded, one mildly and one severely. Cytogenetic studies showed a high percentage of lymphocytes with the fragile X chromosome and inactivation occurring preferentially in the normal X chromosome. Autism is shown to be a severe behavioral and cognitive manifestation of the fragile X syndrome in females.

AB - We present two women with the fragile X syndrome (Martin-Bell syndrome) and autism. Both are mentally retarded, one mildly and one severely. Cytogenetic studies showed a high percentage of lymphocytes with the fragile X chromosome and inactivation occurring preferentially in the normal X chromosome. Autism is shown to be a severe behavioral and cognitive manifestation of the fragile X syndrome in females.

UR - http://www.scopus.com/inward/record.url?scp=0022610146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022610146&partnerID=8YFLogxK

M3 - Article

C2 - 3953655

AN - SCOPUS:0022610146

VL - 23

SP - 375

EP - 380

JO - American Journal of Medical Genetics

JF - American Journal of Medical Genetics

SN - 1552-4825

IS - 1-2

ER -

Autism in fragile X females

Abstract

ASJC Scopus subject areas

Other files and links

Cite this