Abstract
Carter Cameron S., Lynn C. Robertson, Marc R. Chaderjian, Linda O'ShoraCelaya and Thomas E. Nordahl : Attentional Asymmetry in Scizophrenia: The Role of Illness Subtype and Symptomatology. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1994, 18: 3 661-683. 1. Patients with undifferentiated and paranoid schizophrenia, and normal controls were compared using 2 versions of the covert orienting of attention procedure which evaluate exogenous (automatic) and endogenous (controlled) cuing mechanisms. 2. For both tasks, attentional performance varied with illness subtype, but in different ways. 3. On measures of automatic orienting undifferentiated patients showed evidence consistent with a mild right visual field deficit, while paranoid showed a reduction of inhibition-of-return, a mechanism which biases against returning to previously attended locations. 4. On measures of controlled orienting only the undifferentiated group showed the asymmetry of costs which has been the emphasis of most previous studies. The pattern of cost asymmetry was similar to that previously associated with prominent negative symptoms. Additionally, the magnitude of cost asymmetry correlated positively with negative symptoms in the overall patient group. 5. These findings show that systematically considering cue type and symptomatology are critical in interpreting varying patterns of performance by different groups of patients with schizophrenia on the covert orienting procedure. The implications of these findings for understanding the psychopathology of attention in schizophrenia and its neurobiological substrates are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 661-683 |
| Number of pages | 23 |
| Journal | Progress in Neuropsychopharmacology and Biological Psychiatry |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1994 |
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Keywords
- attention
- covert orienting
- reaction time
- schizophrenia
- symptomatology
ASJC Scopus subject areas
- Biological Psychiatry
- Pharmacology
Cite this
Attentional asymmetry in schizophrenia : The role of illness subtype and symptomatology. / Carter, Cameron S; Robertson, Lynn C.; Chaderjian, Marc R.; O'Shora-Celaya, Linda; Nordahl, Thomas E.
In: Progress in Neuropsychopharmacology and Biological Psychiatry, Vol. 18, No. 4, 1994, p. 661-683.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Attentional asymmetry in schizophrenia
T2 - The role of illness subtype and symptomatology
AU - Carter, Cameron S
AU - Robertson, Lynn C.
AU - Chaderjian, Marc R.
AU - O'Shora-Celaya, Linda
AU - Nordahl, Thomas E
PY - 1994
Y1 - 1994
N2 - Carter Cameron S., Lynn C. Robertson, Marc R. Chaderjian, Linda O'ShoraCelaya and Thomas E. Nordahl : Attentional Asymmetry in Scizophrenia: The Role of Illness Subtype and Symptomatology. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1994, 18: 3 661-683. 1. Patients with undifferentiated and paranoid schizophrenia, and normal controls were compared using 2 versions of the covert orienting of attention procedure which evaluate exogenous (automatic) and endogenous (controlled) cuing mechanisms. 2. For both tasks, attentional performance varied with illness subtype, but in different ways. 3. On measures of automatic orienting undifferentiated patients showed evidence consistent with a mild right visual field deficit, while paranoid showed a reduction of inhibition-of-return, a mechanism which biases against returning to previously attended locations. 4. On measures of controlled orienting only the undifferentiated group showed the asymmetry of costs which has been the emphasis of most previous studies. The pattern of cost asymmetry was similar to that previously associated with prominent negative symptoms. Additionally, the magnitude of cost asymmetry correlated positively with negative symptoms in the overall patient group. 5. These findings show that systematically considering cue type and symptomatology are critical in interpreting varying patterns of performance by different groups of patients with schizophrenia on the covert orienting procedure. The implications of these findings for understanding the psychopathology of attention in schizophrenia and its neurobiological substrates are discussed.
AB - Carter Cameron S., Lynn C. Robertson, Marc R. Chaderjian, Linda O'ShoraCelaya and Thomas E. Nordahl : Attentional Asymmetry in Scizophrenia: The Role of Illness Subtype and Symptomatology. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1994, 18: 3 661-683. 1. Patients with undifferentiated and paranoid schizophrenia, and normal controls were compared using 2 versions of the covert orienting of attention procedure which evaluate exogenous (automatic) and endogenous (controlled) cuing mechanisms. 2. For both tasks, attentional performance varied with illness subtype, but in different ways. 3. On measures of automatic orienting undifferentiated patients showed evidence consistent with a mild right visual field deficit, while paranoid showed a reduction of inhibition-of-return, a mechanism which biases against returning to previously attended locations. 4. On measures of controlled orienting only the undifferentiated group showed the asymmetry of costs which has been the emphasis of most previous studies. The pattern of cost asymmetry was similar to that previously associated with prominent negative symptoms. Additionally, the magnitude of cost asymmetry correlated positively with negative symptoms in the overall patient group. 5. These findings show that systematically considering cue type and symptomatology are critical in interpreting varying patterns of performance by different groups of patients with schizophrenia on the covert orienting procedure. The implications of these findings for understanding the psychopathology of attention in schizophrenia and its neurobiological substrates are discussed.
KW - attention
KW - covert orienting
KW - reaction time
KW - schizophrenia
KW - symptomatology
UR - http://www.scopus.com/inward/record.url?scp=0028024078&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028024078&partnerID=8YFLogxK
U2 - 10.1016/0278-5846(94)90075-2
DO - 10.1016/0278-5846(94)90075-2
M3 - Article
C2 - 7938558
AN - SCOPUS:0028024078
VL - 18
SP - 661
EP - 683
JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry
JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry
SN - 0278-5846
IS - 4
ER -