Asthma in exercising children exposed to ozone: A cohort study

Rob McConnell, Kiros Berhane, Frank Gilliland, Stephanie J. London, Talat Islam, W. James Gauderman, Edward Avol, Helene G Margolis, John M. Peters

Research output: Contribution to journalArticle

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Abstract

Background: Little is known about the effect of exposure to air pollution during exercise or time spent outdoors on the development of asthma. We investigated the relation between newly-diagnosed asthma and team sports in a cohort of children exposed to different concentrations and mixtures of air pollutants. Methods: 3535 children with no history of asthma were recruited from schools in 12 communities in southern California and were followed up for up to 5 years. 265 children reported a new diagnosis of asthma during follow-up. We assessed risk of asthma in children playing team sports at study entry in six communities with high daytime ozone concentrations, six with lower concentrations, and in communities with high or low concentrations of nitrogen dioxide, particulate matter, and inorganic-acid vapour. Findings: In communities with high ozone concentrations, the relative risk of developing asthma in children playing three or more sports was 3.3 (95% CI 1.9-5.8), compared with children playing no sports. Sports had no effect in areas of low ozone concentration (0.8, 0.4-1.6). Time spent outside was associated with a higher incidence of asthma in areas of high ozone (1.4, 1.0-2.1), but not in areas of low ozone. Exposure to pollutants other than ozone did not alter the effect of team sports. Interpretation: Incidence of new diagnoses of asthma is associated with heavy exercise in communities with high concentrations of ozone, thus, air pollution and outdoor exercise could contribute to the development of asthma in children.

Original languageEnglish (US)
Pages (from-to)386-391
Number of pages6
JournalLancet
Volume359
Issue number9304
DOIs
StatePublished - Feb 2 2002

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Ozone
Cohort Studies
Asthma
Sports
Air Pollution
Exercise
Nitrogen Dioxide
Air Pollutants
Particulate Matter
Incidence
Acids

ASJC Scopus subject areas

  • Medicine(all)

Cite this

McConnell, R., Berhane, K., Gilliland, F., London, S. J., Islam, T., Gauderman, W. J., ... Peters, J. M. (2002). Asthma in exercising children exposed to ozone: A cohort study. Lancet, 359(9304), 386-391. https://doi.org/10.1016/S0140-6736(02)07597-9

Asthma in exercising children exposed to ozone : A cohort study. / McConnell, Rob; Berhane, Kiros; Gilliland, Frank; London, Stephanie J.; Islam, Talat; Gauderman, W. James; Avol, Edward; Margolis, Helene G; Peters, John M.

In: Lancet, Vol. 359, No. 9304, 02.02.2002, p. 386-391.

Research output: Contribution to journalArticle

McConnell, R, Berhane, K, Gilliland, F, London, SJ, Islam, T, Gauderman, WJ, Avol, E, Margolis, HG & Peters, JM 2002, 'Asthma in exercising children exposed to ozone: A cohort study', Lancet, vol. 359, no. 9304, pp. 386-391. https://doi.org/10.1016/S0140-6736(02)07597-9
McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ et al. Asthma in exercising children exposed to ozone: A cohort study. Lancet. 2002 Feb 2;359(9304):386-391. https://doi.org/10.1016/S0140-6736(02)07597-9
McConnell, Rob ; Berhane, Kiros ; Gilliland, Frank ; London, Stephanie J. ; Islam, Talat ; Gauderman, W. James ; Avol, Edward ; Margolis, Helene G ; Peters, John M. / Asthma in exercising children exposed to ozone : A cohort study. In: Lancet. 2002 ; Vol. 359, No. 9304. pp. 386-391.
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