Asthma and pregnancy

Rani Reddy Vatti, Suzanne S Teuber

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Asthma is probably the most common serious medical disorder that may complicate pregnancy. A third of pregnant women with asthma will experience worsening of their symptoms, a third will see improvement of their symptoms and a third will see no change. The primary goal is to maintain optimal control of asthma for maternal health and well-being as well as fetal maturation. Vital patient education should cover the use of controller medication, avoidance of asthma triggers and early treatment of asthma exacerbations. Proper asthma management should ideally be started in the preconception period. Since smoking is probably the most modifiable risk factor of asthma, pregnant woman should avoid active and passive smoking. Acute asthma exacerbation during the first trimester is associated with an increased risk of congenital malformations. Poorly controlled asthma is associated with low birth weight, preeclampsia, and preterm birth. Medications used for asthma control in the non-pregnant population are generally the same in pregnancy with a few exceptions. Inhaled corticosteroids (ICS) are the preferred controller therapy. Budesonide is the preferred ICS. Long-acting B-agonists (LABA) are the preferred add-on therapy to medium to high dose ICS. Major triggers for asthma exacerbations during pregnancy are viral infections and ICS nonadherence.

Original languageEnglish (US)
Pages (from-to)45-56
Number of pages12
JournalClinical Reviews in Allergy and Immunology
Volume43
Issue number1-2
DOIs
StatePublished - Aug 2012

Fingerprint

Asthma
Pregnancy
Adrenal Cortex Hormones
Pregnant Women
Budesonide
Tobacco Smoke Pollution
Premature Birth
Low Birth Weight Infant
Virus Diseases
Patient Education
First Pregnancy Trimester
Pre-Eclampsia
Therapeutics
Smoking
Population

Keywords

  • Asthma
  • Congenital abnormalities
  • Pregnancy
  • Prenatal
  • Treatment

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Asthma and pregnancy. / Vatti, Rani Reddy; Teuber, Suzanne S.

In: Clinical Reviews in Allergy and Immunology, Vol. 43, No. 1-2, 08.2012, p. 45-56.

Research output: Contribution to journalArticle

Vatti, Rani Reddy ; Teuber, Suzanne S. / Asthma and pregnancy. In: Clinical Reviews in Allergy and Immunology. 2012 ; Vol. 43, No. 1-2. pp. 45-56.
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