Associations between mental disorders and subsequent onset of hypertension

Dan J. Stein, Sergio Aguilar-Gaxiola, Jordi Alonso, Ronny Bruffaerts, Peter De Jonge, Zharoui Liu, Jose Miguel Caldas-de-Almeida, Siobhan O'Neill, Maria Carmen Viana, Ali Obaid Al-Hamzawi, Mattias C. Angermeyer, Corina Benjet, Ron De Graaf, Finola Ferry, Viviane Kovess-Masfety, Daphna Levinson, Giovanni De Girolamo, Silvia Florescu, Chiyi Hu, Norito Kawakami & 8 others Josep Maria Haro, Marina Piazza, Jose Posada-Villa, Bogdan J. Wojtyniak, Miguel Xavier, Carmen C W Lim, Ronald C. Kessler, Kate M. Scott

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Background: Previous work has suggested significant associations between various psychological symptoms (e.g., depression, anxiety, anger, alcohol abuse) and hypertension. However, the presence and extent of associations between common mental disorders and subsequent adult onset of hypertension remain unclear. Further, there are few data available on how such associations vary by gender or over life course. Methods: Data from the World Mental Health Surveys (comprising 19 countries and 52,095 adults) were used. Survival analyses estimated associations between first onset of common mental disorders and subsequent onset of hypertension, with and without psychiatric comorbidity adjustment. Variations in the strength of associations by gender and by life course stage of onset of both the mental disorder and hypertension were investigated. Results: After psychiatric comorbidity adjustment, depression, panic disorder, social phobia, specific phobia, binge eating disorder, bulimia nervosa, alcohol abuse and drug abuse were significantly associated with subsequent diagnosis of hypertension (with odds ratios ranging from 1.1 to 1.6). Number of lifetime mental disorders was associated with subsequent hypertension in a dose-response fashion. For social phobia and alcohol abuse, associations with hypertension were stronger for males than females. For panic disorder, the association with hypertension was particularly apparent in earlier-onset hypertension. Conclusions: Depression, anxiety, impulsive eating disorders and substance use disorders were significantly associated with the subsequent diagnosis of hypertension. These data underscore the importance of early detection of mental disorders, and of physical health monitoring in people with these conditions.

Original languageEnglish (US)
Pages (from-to)142-149
Number of pages8
JournalGeneral Hospital Psychiatry
Volume36
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Mental Disorders
Hypertension
Alcoholism
Social Adjustment
Panic Disorder
Depression
Substance-Related Disorders
Psychiatry
Comorbidity
Anxiety
Binge-Eating Disorder
Bulimia Nervosa
Anger
Survival Analysis
Health Surveys
Mental Health
Odds Ratio
Psychology
Health

Keywords

  • Common mental disorders
  • Hypertension
  • World mental health surveys

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Associations between mental disorders and subsequent onset of hypertension. / Stein, Dan J.; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Bruffaerts, Ronny; De Jonge, Peter; Liu, Zharoui; Miguel Caldas-de-Almeida, Jose; O'Neill, Siobhan; Viana, Maria Carmen; Al-Hamzawi, Ali Obaid; Angermeyer, Mattias C.; Benjet, Corina; De Graaf, Ron; Ferry, Finola; Kovess-Masfety, Viviane; Levinson, Daphna; De Girolamo, Giovanni; Florescu, Silvia; Hu, Chiyi; Kawakami, Norito; Maria Haro, Josep; Piazza, Marina; Posada-Villa, Jose; Wojtyniak, Bogdan J.; Xavier, Miguel; Lim, Carmen C W; Kessler, Ronald C.; Scott, Kate M.

In: General Hospital Psychiatry, Vol. 36, No. 2, 2014, p. 142-149.

Research output: Contribution to journalArticle

Stein, DJ, Aguilar-Gaxiola, S, Alonso, J, Bruffaerts, R, De Jonge, P, Liu, Z, Miguel Caldas-de-Almeida, J, O'Neill, S, Viana, MC, Al-Hamzawi, AO, Angermeyer, MC, Benjet, C, De Graaf, R, Ferry, F, Kovess-Masfety, V, Levinson, D, De Girolamo, G, Florescu, S, Hu, C, Kawakami, N, Maria Haro, J, Piazza, M, Posada-Villa, J, Wojtyniak, BJ, Xavier, M, Lim, CCW, Kessler, RC & Scott, KM 2014, 'Associations between mental disorders and subsequent onset of hypertension', General Hospital Psychiatry, vol. 36, no. 2, pp. 142-149. https://doi.org/10.1016/j.genhosppsych.2013.11.002
Stein, Dan J. ; Aguilar-Gaxiola, Sergio ; Alonso, Jordi ; Bruffaerts, Ronny ; De Jonge, Peter ; Liu, Zharoui ; Miguel Caldas-de-Almeida, Jose ; O'Neill, Siobhan ; Viana, Maria Carmen ; Al-Hamzawi, Ali Obaid ; Angermeyer, Mattias C. ; Benjet, Corina ; De Graaf, Ron ; Ferry, Finola ; Kovess-Masfety, Viviane ; Levinson, Daphna ; De Girolamo, Giovanni ; Florescu, Silvia ; Hu, Chiyi ; Kawakami, Norito ; Maria Haro, Josep ; Piazza, Marina ; Posada-Villa, Jose ; Wojtyniak, Bogdan J. ; Xavier, Miguel ; Lim, Carmen C W ; Kessler, Ronald C. ; Scott, Kate M. / Associations between mental disorders and subsequent onset of hypertension. In: General Hospital Psychiatry. 2014 ; Vol. 36, No. 2. pp. 142-149.
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AU - Stein, Dan J.

AU - Aguilar-Gaxiola, Sergio

AU - Alonso, Jordi

AU - Bruffaerts, Ronny

AU - De Jonge, Peter

AU - Liu, Zharoui

AU - Miguel Caldas-de-Almeida, Jose

AU - O'Neill, Siobhan

AU - Viana, Maria Carmen

AU - Al-Hamzawi, Ali Obaid

AU - Angermeyer, Mattias C.

AU - Benjet, Corina

AU - De Graaf, Ron

AU - Ferry, Finola

AU - Kovess-Masfety, Viviane

AU - Levinson, Daphna

AU - De Girolamo, Giovanni

AU - Florescu, Silvia

AU - Hu, Chiyi

AU - Kawakami, Norito

AU - Maria Haro, Josep

AU - Piazza, Marina

AU - Posada-Villa, Jose

AU - Wojtyniak, Bogdan J.

AU - Xavier, Miguel

AU - Lim, Carmen C W

AU - Kessler, Ronald C.

AU - Scott, Kate M.

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N2 - Background: Previous work has suggested significant associations between various psychological symptoms (e.g., depression, anxiety, anger, alcohol abuse) and hypertension. However, the presence and extent of associations between common mental disorders and subsequent adult onset of hypertension remain unclear. Further, there are few data available on how such associations vary by gender or over life course. Methods: Data from the World Mental Health Surveys (comprising 19 countries and 52,095 adults) were used. Survival analyses estimated associations between first onset of common mental disorders and subsequent onset of hypertension, with and without psychiatric comorbidity adjustment. Variations in the strength of associations by gender and by life course stage of onset of both the mental disorder and hypertension were investigated. Results: After psychiatric comorbidity adjustment, depression, panic disorder, social phobia, specific phobia, binge eating disorder, bulimia nervosa, alcohol abuse and drug abuse were significantly associated with subsequent diagnosis of hypertension (with odds ratios ranging from 1.1 to 1.6). Number of lifetime mental disorders was associated with subsequent hypertension in a dose-response fashion. For social phobia and alcohol abuse, associations with hypertension were stronger for males than females. For panic disorder, the association with hypertension was particularly apparent in earlier-onset hypertension. Conclusions: Depression, anxiety, impulsive eating disorders and substance use disorders were significantly associated with the subsequent diagnosis of hypertension. These data underscore the importance of early detection of mental disorders, and of physical health monitoring in people with these conditions.

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