Associations between Campylobacter fetus, Haemophilus somnus, Leptospira hardjo and bovine viral diarrhea virus antibody titers in dairy cattle from a California herd

Saeed Akhtar, Thomas B Farver, Hans P. Riemann

Research output: Contribution to journalArticle

Abstract

In a cross-sectional study, the associations of age, serological status against Campylobacter fetus (CF), Haemophilus somnus (HS) and Leptospira hardjo (LH) with the seroprevalence of bovine viral diarrhea virus (BVDV) in dairy cattle were evaluated. Six hundred and thirty cattle from a herd in Tulare county of California were included in the study. Blood samples from the cattle were collected in December 1986. Enzyme-linked immunosorbant assay (ELISA) was used to determine the positive or negative status of cows against CF, HS, LH and BVDV antigens. Loglinear analysis was used to describe the relationships of four categorical variables with the seroprevalence of BVDV. The final loglinear model was interpreted as a logit model and obtained by conditioning on explanatory variables in the model found to relate significantly with BVDV seropositivity. The hierarchical logit model included two two-way interactions (BVDV × HS and BVDV × LH) and a three-way interaction (BVDV × CF × age). HS-seronegative cattle had 4.7 times greater odds of being BVDV-seropositive compared with HS-seropositive cattle. In contrast, LH-seropositive cattle had 2.7 times increased odds of BVDV seropositivity compared with LH-seronegative cattle. The presence of the three-way interaction term in the model involving age, CF and BVDV seroprevalence implies that among heifers, CF-seronegative and CF-seropositive animals had about the same odds of BVDV seropositivity (e.g. adjusted odds ratios = 20.5 vs. 24.5), whereas, among cows, CF-seronegative animals had at least twice the odds of being BVDV-seropositive than those of CF-seropositive animals (e.g. adjusted odds ratios = 23.0 vs. 11.0).

Original languageEnglish (US)
Pages (from-to)125-134
Number of pages10
JournalPreventive Veterinary Medicine
Volume27
Issue number3-4
StatePublished - Jul 1996

Fingerprint

Haemophilus somnus
Campylobacter fetus
Leptospira interrogans serovar hardjo
Bovine Viral Diarrhea Viruses
Leptospira
Bovine viral diarrhea virus
Viral Load
dairy cattle
herds
antibodies
Antibodies
seroprevalence
cattle
Seroepidemiologic Studies
logit analysis
odds ratio
Logistic Models
Odds Ratio
cows
animals

Keywords

  • Bovine viral diarrhea virus
  • Campylobacter fetus
  • Haemophilus somnus
  • Leptospira hardjo
  • Loglinear model
  • Serology

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

@article{b058706e7fca40b1bbf0649fc090d754,
title = "Associations between Campylobacter fetus, Haemophilus somnus, Leptospira hardjo and bovine viral diarrhea virus antibody titers in dairy cattle from a California herd",
abstract = "In a cross-sectional study, the associations of age, serological status against Campylobacter fetus (CF), Haemophilus somnus (HS) and Leptospira hardjo (LH) with the seroprevalence of bovine viral diarrhea virus (BVDV) in dairy cattle were evaluated. Six hundred and thirty cattle from a herd in Tulare county of California were included in the study. Blood samples from the cattle were collected in December 1986. Enzyme-linked immunosorbant assay (ELISA) was used to determine the positive or negative status of cows against CF, HS, LH and BVDV antigens. Loglinear analysis was used to describe the relationships of four categorical variables with the seroprevalence of BVDV. The final loglinear model was interpreted as a logit model and obtained by conditioning on explanatory variables in the model found to relate significantly with BVDV seropositivity. The hierarchical logit model included two two-way interactions (BVDV × HS and BVDV × LH) and a three-way interaction (BVDV × CF × age). HS-seronegative cattle had 4.7 times greater odds of being BVDV-seropositive compared with HS-seropositive cattle. In contrast, LH-seropositive cattle had 2.7 times increased odds of BVDV seropositivity compared with LH-seronegative cattle. The presence of the three-way interaction term in the model involving age, CF and BVDV seroprevalence implies that among heifers, CF-seronegative and CF-seropositive animals had about the same odds of BVDV seropositivity (e.g. adjusted odds ratios = 20.5 vs. 24.5), whereas, among cows, CF-seronegative animals had at least twice the odds of being BVDV-seropositive than those of CF-seropositive animals (e.g. adjusted odds ratios = 23.0 vs. 11.0).",
keywords = "Bovine viral diarrhea virus, Campylobacter fetus, Haemophilus somnus, Leptospira hardjo, Loglinear model, Serology",
author = "Saeed Akhtar and Farver, {Thomas B} and Riemann, {Hans P.}",
year = "1996",
month = "7",
language = "English (US)",
volume = "27",
pages = "125--134",
journal = "Preventive Veterinary Medicine",
issn = "0167-5877",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - Associations between Campylobacter fetus, Haemophilus somnus, Leptospira hardjo and bovine viral diarrhea virus antibody titers in dairy cattle from a California herd

AU - Akhtar, Saeed

AU - Farver, Thomas B

AU - Riemann, Hans P.

PY - 1996/7

Y1 - 1996/7

N2 - In a cross-sectional study, the associations of age, serological status against Campylobacter fetus (CF), Haemophilus somnus (HS) and Leptospira hardjo (LH) with the seroprevalence of bovine viral diarrhea virus (BVDV) in dairy cattle were evaluated. Six hundred and thirty cattle from a herd in Tulare county of California were included in the study. Blood samples from the cattle were collected in December 1986. Enzyme-linked immunosorbant assay (ELISA) was used to determine the positive or negative status of cows against CF, HS, LH and BVDV antigens. Loglinear analysis was used to describe the relationships of four categorical variables with the seroprevalence of BVDV. The final loglinear model was interpreted as a logit model and obtained by conditioning on explanatory variables in the model found to relate significantly with BVDV seropositivity. The hierarchical logit model included two two-way interactions (BVDV × HS and BVDV × LH) and a three-way interaction (BVDV × CF × age). HS-seronegative cattle had 4.7 times greater odds of being BVDV-seropositive compared with HS-seropositive cattle. In contrast, LH-seropositive cattle had 2.7 times increased odds of BVDV seropositivity compared with LH-seronegative cattle. The presence of the three-way interaction term in the model involving age, CF and BVDV seroprevalence implies that among heifers, CF-seronegative and CF-seropositive animals had about the same odds of BVDV seropositivity (e.g. adjusted odds ratios = 20.5 vs. 24.5), whereas, among cows, CF-seronegative animals had at least twice the odds of being BVDV-seropositive than those of CF-seropositive animals (e.g. adjusted odds ratios = 23.0 vs. 11.0).

AB - In a cross-sectional study, the associations of age, serological status against Campylobacter fetus (CF), Haemophilus somnus (HS) and Leptospira hardjo (LH) with the seroprevalence of bovine viral diarrhea virus (BVDV) in dairy cattle were evaluated. Six hundred and thirty cattle from a herd in Tulare county of California were included in the study. Blood samples from the cattle were collected in December 1986. Enzyme-linked immunosorbant assay (ELISA) was used to determine the positive or negative status of cows against CF, HS, LH and BVDV antigens. Loglinear analysis was used to describe the relationships of four categorical variables with the seroprevalence of BVDV. The final loglinear model was interpreted as a logit model and obtained by conditioning on explanatory variables in the model found to relate significantly with BVDV seropositivity. The hierarchical logit model included two two-way interactions (BVDV × HS and BVDV × LH) and a three-way interaction (BVDV × CF × age). HS-seronegative cattle had 4.7 times greater odds of being BVDV-seropositive compared with HS-seropositive cattle. In contrast, LH-seropositive cattle had 2.7 times increased odds of BVDV seropositivity compared with LH-seronegative cattle. The presence of the three-way interaction term in the model involving age, CF and BVDV seroprevalence implies that among heifers, CF-seronegative and CF-seropositive animals had about the same odds of BVDV seropositivity (e.g. adjusted odds ratios = 20.5 vs. 24.5), whereas, among cows, CF-seronegative animals had at least twice the odds of being BVDV-seropositive than those of CF-seropositive animals (e.g. adjusted odds ratios = 23.0 vs. 11.0).

KW - Bovine viral diarrhea virus

KW - Campylobacter fetus

KW - Haemophilus somnus

KW - Leptospira hardjo

KW - Loglinear model

KW - Serology

UR - http://www.scopus.com/inward/record.url?scp=30244478170&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30244478170&partnerID=8YFLogxK

M3 - Article

VL - 27

SP - 125

EP - 134

JO - Preventive Veterinary Medicine

JF - Preventive Veterinary Medicine

SN - 0167-5877

IS - 3-4

ER -