Association of low blood manganese concentrations with epilepsy

G. F. Carl, Carl L Keen, B. B. Gallagher, M. S. Clegg, W. H. Littleton, D. B. Flannery, L. S. Hurley

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Abstract

A comparison of hospitalized epileptic patients with matched normals showed that the mean whole blood manganese (Mn) concentration of the epileptic population was significantly lower than the mean of the normal population. The whole blood of Mn concentration in the epileptics did not correlate either with seizure frequency or with anticonvulsant therapy. It was observed, however, that patients whose epilepsy was a result of trauma had significantly higher blood Mn concentrations than patients whose history was negative for trauma.

Original languageEnglish (US)
Pages (from-to)1584-1587
Number of pages4
JournalNeurology
Volume36
Issue number12
StatePublished - 1986

ASJC Scopus subject areas

  • Neuroscience(all)

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    Carl, G. F., Keen, C. L., Gallagher, B. B., Clegg, M. S., Littleton, W. H., Flannery, D. B., & Hurley, L. S. (1986). Association of low blood manganese concentrations with epilepsy. Neurology, 36(12), 1584-1587.