Abstract
Objective: To evaluate the relationship of hip radiographic osteoarthritis (ROA) and MRI findings of cartilage lesions, labral tears, bone marrow edema-like lesions (BMELs) and subchondral cysts with self-reported and physical function. Design: Eighty five subjects were classified as controls (n=55, Kellgren-Lawrence (KL) 0, 1) or having mild-moderate ROA (n=30, KL 2, 3). T2 weighted MRI images at 3-Twere graded for presence of cartilage lesions, labral tears, BMELs and subchondral cysts. Posterior wall sign, cross-over sign, center-edge angle and alpha angle were also recorded. Function was assessed using Hip dysfunction and Osteoarthritis Outcome Score (HOOS), Timed-Up and Go (TUG) test and Y-Balance Test (YBT). Analysis compared function between subjects with and without ROA and those with and without femoral or acetabular cartilage lesions, adjusted for age. Non-parametric correlations were used to assess the relationship between radiographic scores, MRI scores and function. Results: Subjects with acetabular cartilage lesions had worse HOOS (Difference=5-10%, P=0.036-0.004), but not TUG or YBT, scores. Acetabular cartilage lesions, BMELs and subchondral cysts were associated with worse HOOS scores (ρ=0.23-0.37, P=0.041-0.001). Differences in function between subjects with and without ROA or femoral cartilage lesions were not significant. Other radiologic findings were not associated with function. Conclusions: Acetabular cartilage defects, but not femoral cartilage defects or ROA, were associated with greater self-reported pain and disability. BMELs and subchondral cysts were related to greater hip related self-reported pain and disability. None of the radiographic or MRI features was related to physical function.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1685-1692 |
| Number of pages | 8 |
| Journal | Osteoarthritis and Cartilage |
| Volume | 21 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2013 |
| Externally published | Yes |
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Keywords
- Balance
- BMEL
- Kellgren-Lawrence
- Labral tears
- Subchondral cyst
- Y-Balance Test
ASJC Scopus subject areas
- Rheumatology
- Orthopedics and Sports Medicine
- Biomedical Engineering
Cite this
Association of cartilage defects, and other MRI findings with pain and function in individuals with mild-moderate radiographic hip osteoarthritis and controls. / Kumar, D.; Wyatt, C. R.; Lee, S.; Nardo, Lorenzo; Link, T. M.; Majumdar, S.; Souza, R. B.
In: Osteoarthritis and Cartilage, Vol. 21, No. 11, 01.11.2013, p. 1685-1692.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association of cartilage defects, and other MRI findings with pain and function in individuals with mild-moderate radiographic hip osteoarthritis and controls
AU - Kumar, D.
AU - Wyatt, C. R.
AU - Lee, S.
AU - Nardo, Lorenzo
AU - Link, T. M.
AU - Majumdar, S.
AU - Souza, R. B.
PY - 2013/11/1
Y1 - 2013/11/1
N2 - Objective: To evaluate the relationship of hip radiographic osteoarthritis (ROA) and MRI findings of cartilage lesions, labral tears, bone marrow edema-like lesions (BMELs) and subchondral cysts with self-reported and physical function. Design: Eighty five subjects were classified as controls (n=55, Kellgren-Lawrence (KL) 0, 1) or having mild-moderate ROA (n=30, KL 2, 3). T2 weighted MRI images at 3-Twere graded for presence of cartilage lesions, labral tears, BMELs and subchondral cysts. Posterior wall sign, cross-over sign, center-edge angle and alpha angle were also recorded. Function was assessed using Hip dysfunction and Osteoarthritis Outcome Score (HOOS), Timed-Up and Go (TUG) test and Y-Balance Test (YBT). Analysis compared function between subjects with and without ROA and those with and without femoral or acetabular cartilage lesions, adjusted for age. Non-parametric correlations were used to assess the relationship between radiographic scores, MRI scores and function. Results: Subjects with acetabular cartilage lesions had worse HOOS (Difference=5-10%, P=0.036-0.004), but not TUG or YBT, scores. Acetabular cartilage lesions, BMELs and subchondral cysts were associated with worse HOOS scores (ρ=0.23-0.37, P=0.041-0.001). Differences in function between subjects with and without ROA or femoral cartilage lesions were not significant. Other radiologic findings were not associated with function. Conclusions: Acetabular cartilage defects, but not femoral cartilage defects or ROA, were associated with greater self-reported pain and disability. BMELs and subchondral cysts were related to greater hip related self-reported pain and disability. None of the radiographic or MRI features was related to physical function.
AB - Objective: To evaluate the relationship of hip radiographic osteoarthritis (ROA) and MRI findings of cartilage lesions, labral tears, bone marrow edema-like lesions (BMELs) and subchondral cysts with self-reported and physical function. Design: Eighty five subjects were classified as controls (n=55, Kellgren-Lawrence (KL) 0, 1) or having mild-moderate ROA (n=30, KL 2, 3). T2 weighted MRI images at 3-Twere graded for presence of cartilage lesions, labral tears, BMELs and subchondral cysts. Posterior wall sign, cross-over sign, center-edge angle and alpha angle were also recorded. Function was assessed using Hip dysfunction and Osteoarthritis Outcome Score (HOOS), Timed-Up and Go (TUG) test and Y-Balance Test (YBT). Analysis compared function between subjects with and without ROA and those with and without femoral or acetabular cartilage lesions, adjusted for age. Non-parametric correlations were used to assess the relationship between radiographic scores, MRI scores and function. Results: Subjects with acetabular cartilage lesions had worse HOOS (Difference=5-10%, P=0.036-0.004), but not TUG or YBT, scores. Acetabular cartilage lesions, BMELs and subchondral cysts were associated with worse HOOS scores (ρ=0.23-0.37, P=0.041-0.001). Differences in function between subjects with and without ROA or femoral cartilage lesions were not significant. Other radiologic findings were not associated with function. Conclusions: Acetabular cartilage defects, but not femoral cartilage defects or ROA, were associated with greater self-reported pain and disability. BMELs and subchondral cysts were related to greater hip related self-reported pain and disability. None of the radiographic or MRI features was related to physical function.
KW - Balance
KW - BMEL
KW - Kellgren-Lawrence
KW - Labral tears
KW - Subchondral cyst
KW - Y-Balance Test
UR - http://www.scopus.com/inward/record.url?scp=84884975624&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884975624&partnerID=8YFLogxK
U2 - 10.1016/j.joca.2013.08.009
DO - 10.1016/j.joca.2013.08.009
M3 - Article
VL - 21
SP - 1685
EP - 1692
JO - Osteoarthritis and Cartilage
JF - Osteoarthritis and Cartilage
SN - 1063-4584
IS - 11
ER -