Association of body fat distribution with plasma lipids, lipoproteins, apolipoproteins AI and B in postmenopausal women

John T. Soler, Aaron R. Folsom, Lawrence H. Kushi, Ronald J. Prineas, Ulysses S. Seal

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Associations between the distribution of body fat, measured by the waist/hip circumference ratio (WHR), and plasma lipid fractions were examined in 84 postmenopausal women. WHR was correlated r = 0.39 with body mass index (BMI). After adjustment for BMI and other covariates, WHR was positively and significantly associated with concentrations of triglycerides, apolipoprotein B, low-density lipoprotein cholesterol, and the total cholesterol/high density lipoprotein cholesterol ratio. WHR was negatively and significantly associated with concentrations of high density lipoprotein cholesterol and apolipoprotein AI. These results indicate that in postmenopausal women abdominal fat preponderance is associated with an atherogenic plasma lipid profile, independent of its association with BMI.

Original languageEnglish (US)
Pages (from-to)1075-1081
Number of pages7
JournalJournal of Clinical Epidemiology
Volume41
Issue number11
DOIs
StatePublished - 1988
Externally publishedYes

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Keywords

  • Apolipoproteins
  • Body weight
  • Lipids
  • Lipoproteins
  • Obesity

ASJC Scopus subject areas

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

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