Association of bioimpedance spectroscopy-based volume estimation with postdialysis hypotension in patients receiving hemodialysis

Adrian P. Abreo, Glenn M. Chertow, Lorien Dalrymple, George Kaysen, Kirsten L. Johansen

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Clinical examination to determine the dry weight of patients on hemodialysis (HD) has been problematic, with studies showing discordance between physician assessment and objective measures of volume status.We studied the association between predialysis bioimpedance spectroscopy (BIS)-based estimates of fluid overload and postdialysis hypotension in 635 patients in the United States Renal Data System ACTIVE/ADIPOSE (A Cohort study To Investigate the Value of Exercise/Analyses Designed to Investigate the Paradox of Obesity and Survival in ESRD) study receiving HD in 2009-2011. We recorded predialysis and postdialysis weight and blood pressures over 3 consecutive HD sessions and performed BIS before a single session. Using a previously reported method of estimating normohydration weight, we estimated postdialysis fluid overload (FOpost) in liters. We used logistic regression with extracellular water/total body water (ECW/TBW) or estimated FOpost as the primary predictor and 1 or more postdialysis systolic blood pressures less than 110mmHg as the dependent variable. Models were adjusted for age, sex, race, ultrafiltration rate per kilogram of body weight, end-stage renal disease vintage, diabetes mellitus, heart failure, and albumin. Higher ECW/TBW was associated with lower odds of postdialysis hypotension (odds ratio [OR] 0.35, 95% confidence interval [CI] 0.15-0.84 per 0.1, P=0.02). Every liter of FOpost was associated with lower adjusted odds of postdialysis hypotension (OR 0.86, 95% CI 0.79-0.95, P=0.003). Prospective studies are needed to determine whether this application of BIS could improve current clinical efforts to minimize episodes of postdialysis hypotension without leading to volume overload.

Original languageEnglish (US)
Pages (from-to)536-542
Number of pages7
JournalHemodialysis International
Volume19
Issue number4
DOIs
StatePublished - Oct 1 2015

Fingerprint

Hypotension
Renal Dialysis
Spectrum Analysis
Body Water
Blood Pressure
Weights and Measures
Chronic Kidney Failure
Odds Ratio
Confidence Intervals
Water
Ultrafiltration
Information Systems
Albumins
Diabetes Mellitus
Cohort Studies
Heart Failure
Obesity
Logistic Models
Body Weight
Prospective Studies

Keywords

  • Bioimpedance spectroscopy
  • End-stage renal disease
  • Hemodialysis
  • Volume status

ASJC Scopus subject areas

  • Hematology
  • Nephrology

Cite this

Association of bioimpedance spectroscopy-based volume estimation with postdialysis hypotension in patients receiving hemodialysis. / Abreo, Adrian P.; Chertow, Glenn M.; Dalrymple, Lorien; Kaysen, George; Johansen, Kirsten L.

In: Hemodialysis International, Vol. 19, No. 4, 01.10.2015, p. 536-542.

Research output: Contribution to journalArticle

Abreo, Adrian P. ; Chertow, Glenn M. ; Dalrymple, Lorien ; Kaysen, George ; Johansen, Kirsten L. / Association of bioimpedance spectroscopy-based volume estimation with postdialysis hypotension in patients receiving hemodialysis. In: Hemodialysis International. 2015 ; Vol. 19, No. 4. pp. 536-542.
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