Association between environmental factors including second-hand smoke and primary lung cancer in dogs

A. Zierenberg-Ripoll, Rachel E Pollard, Susan L Stewart, S. D. Allstadt, L. E. Barrett, J. M. Gillem, Katherine A Skorupski

Research output: Contribution to journalArticle

Abstract

Objectives: To estimate prevalence of exposure to environmental tobacco smoke and other environmental toxins in dogs with primary lung tumours and to analyse association between exposure and lung tumour development. Materials and Methods: In this case–control study, an owner survey was developed to collect data on patient characteristics, general health care and environmental exposures. Dogs diagnosed with primary lung carcinomas formed the Case group. Dogs diagnosed with mast cell tumours served as Control Group 1 and dogs diagnosed with neurologic disease served as Control Group 2. Associations between diagnosis of primary lung tumour and patient and environmental exposure variables were analysed using bivariate and multivariate statistical methods. Results: A total of 1178 owner surveys were mailed and 470 surveys were returned and included in statistical analysis, including 135 Cases, 169 dogs in Control Group 1 and 166 dogs in Control Group 2. An association between exposure to second-hand smoke and prevalence of primary lung cancer was not identified in this study. Clinical Significance: Second-hand smoke is associated with primary lung cancer in people but a definitive association has not been found in dogs. The results of this study suggest that tobacco smoke exposure may not be associated with primary lung cancer development in dogs but study limitations may have precluded detection of an association.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalJournal of Small Animal Practice
Volume59
Issue number6
DOIs
StatePublished - Jun 1 2018

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Tobacco Smoke Pollution
lung neoplasms
smoke
Lung Neoplasms
hands
Dogs
environmental factors
dogs
Environmental Exposure
Lung
Control Groups
Smoke
Tobacco
Neoplasms
tobacco
statistical analysis
nervous system diseases
mast cells
Nervous System Diseases
Mast Cells

ASJC Scopus subject areas

  • Small Animals

Cite this

Association between environmental factors including second-hand smoke and primary lung cancer in dogs. / Zierenberg-Ripoll, A.; Pollard, Rachel E; Stewart, Susan L; Allstadt, S. D.; Barrett, L. E.; Gillem, J. M.; Skorupski, Katherine A.

In: Journal of Small Animal Practice, Vol. 59, No. 6, 01.06.2018, p. 343-349.

Research output: Contribution to journalArticle

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