Abstract
Objectives: To assess correlates of bone mineral density (BMD) in older African Americans. Participants: 189 women and 115 men over age 64. Methods: Variables investigated: BMD by dual X-ray absorptiometry (DXA), medications, cardiovascular disease risk factors, demographic, lifestyle factors and functional status. Variables showing univariate correlation with BMD (p≤0.1) were entered into sex-stratified linear regression models. Results: Age range 67-96 (mean 75). The mean BMD (gm/ cm2 ± standard deviation) is reported for three sites. Total body: 1.03 (±0.12) in women, 1.21 (±0.11) in men. Spine: 1.05 (±0.24) in women, 1.22 (±0.26) in men. Total hip: 0.85 (±0.15) in women, 1.04 (±0.17) in men. Gender was significantly associated with BMD (t-test, p<0.001). The R 2 for tested variables were highly significant only for weight. Age was only significant for total hip in women (p0.05). Each kilogram of weight change was associated with a 5.3-6.8 mg/cm2 change in BMD. Conclusions: In a population-based cohort of older African Americans, average BMD was significantly greater in men than women. Weight accounted for most of the explained variability (R2) in BMD; age added little to the overall R2. Lower-weight, older African-American men and women are at significantly increased risk for low BMD and, thus, likely to be at greater risk for osteoporotic fracture.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1609-1615 |
| Number of pages | 7 |
| Journal | Journal of the National Medical Association |
| Volume | 96 |
| Issue number | 12 |
| State | Published - Dec 2004 |
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Keywords
- African Americans
- Elderly
- Osteoporosis
- Weight
ASJC Scopus subject areas
- Medicine(all)
Cite this
Associates of bone mineral density in older African Americans. / Robbins, John A; Hirsch, Calvin H; Cauley, Jane.
In: Journal of the National Medical Association, Vol. 96, No. 12, 12.2004, p. 1609-1615.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Associates of bone mineral density in older African Americans
AU - Robbins, John A
AU - Hirsch, Calvin H
AU - Cauley, Jane
PY - 2004/12
Y1 - 2004/12
N2 - Objectives: To assess correlates of bone mineral density (BMD) in older African Americans. Participants: 189 women and 115 men over age 64. Methods: Variables investigated: BMD by dual X-ray absorptiometry (DXA), medications, cardiovascular disease risk factors, demographic, lifestyle factors and functional status. Variables showing univariate correlation with BMD (p≤0.1) were entered into sex-stratified linear regression models. Results: Age range 67-96 (mean 75). The mean BMD (gm/ cm2 ± standard deviation) is reported for three sites. Total body: 1.03 (±0.12) in women, 1.21 (±0.11) in men. Spine: 1.05 (±0.24) in women, 1.22 (±0.26) in men. Total hip: 0.85 (±0.15) in women, 1.04 (±0.17) in men. Gender was significantly associated with BMD (t-test, p<0.001). The R 2 for tested variables were highly significant only for weight. Age was only significant for total hip in women (p0.05). Each kilogram of weight change was associated with a 5.3-6.8 mg/cm2 change in BMD. Conclusions: In a population-based cohort of older African Americans, average BMD was significantly greater in men than women. Weight accounted for most of the explained variability (R2) in BMD; age added little to the overall R2. Lower-weight, older African-American men and women are at significantly increased risk for low BMD and, thus, likely to be at greater risk for osteoporotic fracture.
AB - Objectives: To assess correlates of bone mineral density (BMD) in older African Americans. Participants: 189 women and 115 men over age 64. Methods: Variables investigated: BMD by dual X-ray absorptiometry (DXA), medications, cardiovascular disease risk factors, demographic, lifestyle factors and functional status. Variables showing univariate correlation with BMD (p≤0.1) were entered into sex-stratified linear regression models. Results: Age range 67-96 (mean 75). The mean BMD (gm/ cm2 ± standard deviation) is reported for three sites. Total body: 1.03 (±0.12) in women, 1.21 (±0.11) in men. Spine: 1.05 (±0.24) in women, 1.22 (±0.26) in men. Total hip: 0.85 (±0.15) in women, 1.04 (±0.17) in men. Gender was significantly associated with BMD (t-test, p<0.001). The R 2 for tested variables were highly significant only for weight. Age was only significant for total hip in women (p0.05). Each kilogram of weight change was associated with a 5.3-6.8 mg/cm2 change in BMD. Conclusions: In a population-based cohort of older African Americans, average BMD was significantly greater in men than women. Weight accounted for most of the explained variability (R2) in BMD; age added little to the overall R2. Lower-weight, older African-American men and women are at significantly increased risk for low BMD and, thus, likely to be at greater risk for osteoporotic fracture.
KW - African Americans
KW - Elderly
KW - Osteoporosis
KW - Weight
UR - http://www.scopus.com/inward/record.url?scp=10344260217&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=10344260217&partnerID=8YFLogxK
M3 - Article
C2 - 15622691
AN - SCOPUS:10344260217
VL - 96
SP - 1609
EP - 1615
JO - Journal of the National Medical Association
JF - Journal of the National Medical Association
SN - 1943-4693
IS - 12
ER -