Assessment of resistance to anoikis in ovarian cancer

Xiaoping He, Jeremy Chien, Viji Shridhar

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

Anoikis, a form of programmed cell death that occurs due to cell detachment from the extracellular matrix, is a critical mechanism in preventing ectopic cell growth. Acquisition of resistance to anoikis is a prerequisite for epithelial ovarian cancer cells to survive in ascitic fluids before forming metastatic foci. Here we describe a colorimetric method for monitoring the resistance of anoikis of ovarian cancer cells in vitro.

Original languageEnglish (US)
Title of host publicationOvarian Cancer
Subtitle of host publicationMethods and Protocols
EditorsAnastasia Malek, Oleg Tchernitsa
Pages347-354
Number of pages8
DOIs
StatePublished - Aug 21 2013
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1049
ISSN (Print)1064-3745

Keywords

  • Anoikis
  • Apoptosis
  • Autophagy
  • Ovarian cancer
  • Tumor metastasis

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    He, X., Chien, J., & Shridhar, V. (2013). Assessment of resistance to anoikis in ovarian cancer. In A. Malek, & O. Tchernitsa (Eds.), Ovarian Cancer: Methods and Protocols (pp. 347-354). (Methods in Molecular Biology; Vol. 1049). https://doi.org/10.1007/978-1-62703-547-7_26