Assessment of regional body composition with dual-energy X-ray absorptiometry in Duchenne muscular dystrophy: Correlation of regional lean mass and quantitative strength

Andrew J. Skalsky, Jay J. Han, Richard T. Abresch, Chris Shin, Craig M McDonald

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

The purpose of this study was to assess regional body composition and its correlation with regional strength in Duchenne muscular dystrophy (DMD) subjects and able-bodied controls. Regional dual-energy X-ray absorptiometry (DEXA) measurements and isometric strength were obtained for 23 DMD subjects and 23 control subjects. DMD subjects showed a decreased regional lean mass (P < 0.001). The correlation between regional strength and regional lean mass was stronger for controls than for DMD subjects. DMD subjects had decreased regional lean mass, increased regional fat mass, and decreased strength.

Original languageEnglish (US)
Pages (from-to)647-651
Number of pages5
JournalMuscle and Nerve
Volume39
Issue number5
DOIs
StatePublished - May 2009

Keywords

  • BMI
  • Body composition
  • Dual-energy X-ray absorptiometry
  • Duchenne muscular dystrophy
  • Fat tissue mass
  • Lean tissue mass
  • Muscle strength

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)
  • Physiology

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