Assessment of patent ductus arteriosus shunting using diastolic pressure analysis

Jay M Milstein, Thomas A. Riemenschneider, Boyd W. Goetzman, Lily George, Richard P. Wennberg

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Ductal shunting significantly affected the time necessary for aortic diastolic pressure to fall to one-halfan initially selected value (t1/2). Fourteen premature infants with clinical evidence of left-to-right ductal shunting had a mean t1/2 of 277 msec (range 133 to 383 msec) compared with a mean t1/2 of 455 msec (range 332 to 567 msec) in 14 neonates with no clinical evidence of ductal shungting (P<0.01). Seven older infants with ductal shunting confirmed at cardiac catheterization had a mean t1/2 of 360 msec (range 240 to 392 msec). Infant catheterization data and animal studies are suggestive of an inverse relationship between the magnitude of shunt and the t1/2. The t1/2 determined by diastolic pressure analysis is a useful method for serial evaluation of ductus arteriosus shunting.

Original languageEnglish (US)
Pages (from-to)122-126
Number of pages5
JournalThe Journal of Pediatrics
Volume94
Issue number1
DOIs
StatePublished - 1979

Fingerprint

Patent Ductus Arteriosus
Blood Pressure
Ductus Arteriosus
Cardiac Catheterization
Premature Infants
Catheterization
Arterial Pressure
Newborn Infant
halofantrine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Assessment of patent ductus arteriosus shunting using diastolic pressure analysis. / Milstein, Jay M; Riemenschneider, Thomas A.; Goetzman, Boyd W.; George, Lily; Wennberg, Richard P.

In: The Journal of Pediatrics, Vol. 94, No. 1, 1979, p. 122-126.

Research output: Contribution to journalArticle

Milstein, Jay M ; Riemenschneider, Thomas A. ; Goetzman, Boyd W. ; George, Lily ; Wennberg, Richard P. / Assessment of patent ductus arteriosus shunting using diastolic pressure analysis. In: The Journal of Pediatrics. 1979 ; Vol. 94, No. 1. pp. 122-126.
@article{8cfa808d53ce4101ad29b4938a08726c,
title = "Assessment of patent ductus arteriosus shunting using diastolic pressure analysis",
abstract = "Ductal shunting significantly affected the time necessary for aortic diastolic pressure to fall to one-halfan initially selected value (t1/2). Fourteen premature infants with clinical evidence of left-to-right ductal shunting had a mean t1/2 of 277 msec (range 133 to 383 msec) compared with a mean t1/2 of 455 msec (range 332 to 567 msec) in 14 neonates with no clinical evidence of ductal shungting (P<0.01). Seven older infants with ductal shunting confirmed at cardiac catheterization had a mean t1/2 of 360 msec (range 240 to 392 msec). Infant catheterization data and animal studies are suggestive of an inverse relationship between the magnitude of shunt and the t1/2. The t1/2 determined by diastolic pressure analysis is a useful method for serial evaluation of ductus arteriosus shunting.",
author = "Milstein, {Jay M} and Riemenschneider, {Thomas A.} and Goetzman, {Boyd W.} and Lily George and Wennberg, {Richard P.}",
year = "1979",
doi = "10.1016/S0022-3476(79)80374-1",
language = "English (US)",
volume = "94",
pages = "122--126",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Assessment of patent ductus arteriosus shunting using diastolic pressure analysis

AU - Milstein, Jay M

AU - Riemenschneider, Thomas A.

AU - Goetzman, Boyd W.

AU - George, Lily

AU - Wennberg, Richard P.

PY - 1979

Y1 - 1979

N2 - Ductal shunting significantly affected the time necessary for aortic diastolic pressure to fall to one-halfan initially selected value (t1/2). Fourteen premature infants with clinical evidence of left-to-right ductal shunting had a mean t1/2 of 277 msec (range 133 to 383 msec) compared with a mean t1/2 of 455 msec (range 332 to 567 msec) in 14 neonates with no clinical evidence of ductal shungting (P<0.01). Seven older infants with ductal shunting confirmed at cardiac catheterization had a mean t1/2 of 360 msec (range 240 to 392 msec). Infant catheterization data and animal studies are suggestive of an inverse relationship between the magnitude of shunt and the t1/2. The t1/2 determined by diastolic pressure analysis is a useful method for serial evaluation of ductus arteriosus shunting.

AB - Ductal shunting significantly affected the time necessary for aortic diastolic pressure to fall to one-halfan initially selected value (t1/2). Fourteen premature infants with clinical evidence of left-to-right ductal shunting had a mean t1/2 of 277 msec (range 133 to 383 msec) compared with a mean t1/2 of 455 msec (range 332 to 567 msec) in 14 neonates with no clinical evidence of ductal shungting (P<0.01). Seven older infants with ductal shunting confirmed at cardiac catheterization had a mean t1/2 of 360 msec (range 240 to 392 msec). Infant catheterization data and animal studies are suggestive of an inverse relationship between the magnitude of shunt and the t1/2. The t1/2 determined by diastolic pressure analysis is a useful method for serial evaluation of ductus arteriosus shunting.

UR - http://www.scopus.com/inward/record.url?scp=0018305179&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018305179&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(79)80374-1

DO - 10.1016/S0022-3476(79)80374-1

M3 - Article

VL - 94

SP - 122

EP - 126

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 1

ER -