Assessment of patent ductus arteriosus shunting using diastolic pressure analysis

Jay M Milstein, Thomas A. Riemenschneider, Boyd W. Goetzman, Lily George, Richard P. Wennberg

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Ductal shunting significantly affected the time necessary for aortic diastolic pressure to fall to one-halfan initially selected value (t1/2). Fourteen premature infants with clinical evidence of left-to-right ductal shunting had a mean t1/2 of 277 msec (range 133 to 383 msec) compared with a mean t1/2 of 455 msec (range 332 to 567 msec) in 14 neonates with no clinical evidence of ductal shungting (P<0.01). Seven older infants with ductal shunting confirmed at cardiac catheterization had a mean t1/2 of 360 msec (range 240 to 392 msec). Infant catheterization data and animal studies are suggestive of an inverse relationship between the magnitude of shunt and the t1/2. The t1/2 determined by diastolic pressure analysis is a useful method for serial evaluation of ductus arteriosus shunting.

Original languageEnglish (US)
Pages (from-to)122-126
Number of pages5
JournalThe Journal of Pediatrics
Volume94
Issue number1
DOIs
StatePublished - 1979

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Milstein, J. M., Riemenschneider, T. A., Goetzman, B. W., George, L., & Wennberg, R. P. (1979). Assessment of patent ductus arteriosus shunting using diastolic pressure analysis. The Journal of Pediatrics, 94(1), 122-126. https://doi.org/10.1016/S0022-3476(79)80374-1