Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide

J. M. Li; J. Xi; L. Zhu; X. F. Chen; W. L. Cao; Mingyu Cheng; Y. D. Gong; N. M. Zhao; X. F. Zhang

Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide

J. M. Li, J. Xi, L. Zhu, X. F. Chen, W. L. Cao, Mingyu Cheng, Y. D. Gong, N. M. Zhao, X. F. Zhang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The modification of chitosan nerve guide to assess nerve function after reconstruction was discussed. Chitosan and M-CHI solution with concentration of 2 wt% and 4 wt% were respectively prepared by dissolution in 0.2 M acetic acid. Female SD rats were anesthetized with 10% chloral hydrate and after 2, 4, 8, 12, 16 weeks of implantation, walking track analysis was carried out to evaluate motor nerve recovery. It was found that all the rats had a regenerated cable inside the conduits, which had bridged a 10mm gap between the nerve stumps.

Original language	English (US)
Title of host publication	Transactions - 7th World Biomaterials Congress
Number of pages	1
State	Published - Dec 1 2004
Externally published	Yes
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: May 17 2004 → May 21 2004

Other

Other	Transactions - 7th World Biomaterials Congress
Country/Territory	Australia
City	Sydney
Period	5/17/04 → 5/21/04

Keywords

Chitin/chitosan
Nerve regeneration

ASJC Scopus subject areas

Engineering(all)

Cite this

@inproceedings{4e60e12581024cbc9f6babbfea3d7fa9,

title = "Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide",

abstract = "The modification of chitosan nerve guide to assess nerve function after reconstruction was discussed. Chitosan and M-CHI solution with concentration of 2 wt% and 4 wt% were respectively prepared by dissolution in 0.2 M acetic acid. Female SD rats were anesthetized with 10% chloral hydrate and after 2, 4, 8, 12, 16 weeks of implantation, walking track analysis was carried out to evaluate motor nerve recovery. It was found that all the rats had a regenerated cable inside the conduits, which had bridged a 10mm gap between the nerve stumps.",

keywords = "Chitin/chitosan, Nerve regeneration",

author = "Li, {J. M.} and J. Xi and L. Zhu and Chen, {X. F.} and Cao, {W. L.} and Mingyu Cheng and Gong, {Y. D.} and Zhao, {N. M.} and Zhang, {X. F.}",

year = "2004",

month = dec,

day = "1",

language = "English (US)",

isbn = "1877040193",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

}

TY - GEN

T1 - Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide

AU - Li, J. M.

AU - Xi, J.

AU - Zhu, L.

AU - Chen, X. F.

AU - Cao, W. L.

AU - Cheng, Mingyu

AU - Gong, Y. D.

AU - Zhao, N. M.

AU - Zhang, X. F.

PY - 2004/12/1

Y1 - 2004/12/1

N2 - The modification of chitosan nerve guide to assess nerve function after reconstruction was discussed. Chitosan and M-CHI solution with concentration of 2 wt% and 4 wt% were respectively prepared by dissolution in 0.2 M acetic acid. Female SD rats were anesthetized with 10% chloral hydrate and after 2, 4, 8, 12, 16 weeks of implantation, walking track analysis was carried out to evaluate motor nerve recovery. It was found that all the rats had a regenerated cable inside the conduits, which had bridged a 10mm gap between the nerve stumps.

AB - The modification of chitosan nerve guide to assess nerve function after reconstruction was discussed. Chitosan and M-CHI solution with concentration of 2 wt% and 4 wt% were respectively prepared by dissolution in 0.2 M acetic acid. Female SD rats were anesthetized with 10% chloral hydrate and after 2, 4, 8, 12, 16 weeks of implantation, walking track analysis was carried out to evaluate motor nerve recovery. It was found that all the rats had a regenerated cable inside the conduits, which had bridged a 10mm gap between the nerve stumps.

KW - Chitin/chitosan

KW - Nerve regeneration

UR - http://www.scopus.com/inward/record.url?scp=13844267540&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844267540&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:13844267540

SN - 1877040193

SN - 9781877040191

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -

Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide

Abstract

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Keywords

ASJC Scopus subject areas

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