Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide

J. M. Li, J. Xi, L. Zhu, X. F. Chen, W. L. Cao, Mingyu Cheng, Y. D. Gong, N. M. Zhao, X. F. Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The modification of chitosan nerve guide to assess nerve function after reconstruction was discussed. Chitosan and M-CHI solution with concentration of 2 wt% and 4 wt% were respectively prepared by dissolution in 0.2 M acetic acid. Female SD rats were anesthetized with 10% chloral hydrate and after 2, 4, 8, 12, 16 weeks of implantation, walking track analysis was carried out to evaluate motor nerve recovery. It was found that all the rats had a regenerated cable inside the conduits, which had bridged a 10mm gap between the nerve stumps.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

Keywords

  • Chitin/chitosan
  • Nerve regeneration

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Li, J. M., Xi, J., Zhu, L., Chen, X. F., Cao, W. L., Cheng, M., Gong, Y. D., Zhao, N. M., & Zhang, X. F. (2004). Assessment of nerve function after reconstruction with a modified porous chitosan nerve guide. In Transactions - 7th World Biomaterials Congress