Assessment of infectious organisms associated with chronic rhinosinusitis in cats

Lynelle R Johnson, Janet E Foley, Hilde E V De Cock, Heather E. Clarke, David J Maggs

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Objective - To determine detection rates for feline herpesvirus type 1 (FHV-1), Mycoplasma spp, fungi, and bacteria in flush samples and biopsy specimens from the nasal cavities of cats with and without chronic rhinosinusitis (CRS). Design - Prospective study. Animals - 10 CRS-affected cats and 7 cats without signs of respiratory tract disease. Procedures - Nasal flush samples and biopsy specimens were collected from all cats for bacterial (aerobic and anaerobic), fungal, and mycoplasmal cultures; additional biopsy specimens were collected for virus isolation and polymerase chain reaction (PCR) assay (to detect FHV-1 DNA). Results - Aerobic bacteria were detected in flush samples from 5 of 7 control cats; culture of flush samples from CRS-affected cats yielded aerobic bacteria (9/10 cats), anaerobic bacteria (3/10), and Mycoplasma spp (2/10). No fungal organisms were isolated from any cat. Potential pathogens were isolated significantly more often from CRS-affected cats than from control cats. Bacterial culture of biopsy specimens yielded aerobic bacteria (2/7 control cats and 4/10 CRS-affected cats) and anaerobic bacteria (2/10 CRS-affected cats). Although FHV-1 was not detected in nasal biopsy specimens from control or CRS-affected cats, FHV-1 DNA was detected via PCR assay in specimens from 4 of 7 control cats and 3 of 10 CRS-affected cats. Conclusions and Clinical Relevance - Compared with findings in control cats, anaerobic bacteria, Mycoplasma spp, and a variety of potentially pathogenic organisms were detected more commonly in samples from cats with CRS. In both groups, FHV-1 was detected via PCR assay as a nonviable organism or in noncultivable amounts.

Original languageEnglish (US)
Pages (from-to)579-585
Number of pages7
JournalJournal of the American Veterinary Medical Association
Volume227
Issue number4
DOIs
StatePublished - Aug 15 2005

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Cats
cats
organisms
Felid herpesvirus 1
Herpesviridae
Felidae
biopsy
bacteria
Aerobic Bacteria
Anaerobic Bacteria
Mycoplasma
Biopsy
polymerase chain reaction
Nose
Polymerase Chain Reaction
sampling
assays
Respiratory Tract Diseases
fungi
nasal cavity

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Assessment of infectious organisms associated with chronic rhinosinusitis in cats. / Johnson, Lynelle R; Foley, Janet E; De Cock, Hilde E V; Clarke, Heather E.; Maggs, David J.

In: Journal of the American Veterinary Medical Association, Vol. 227, No. 4, 15.08.2005, p. 579-585.

Research output: Contribution to journalArticle

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