Assessment of coronary artery stent patency by electron-beam CT

Friedrich D Knollmann, Jörg Möller, Axel Gebert, Christian Bethge, Roland Felix

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Following coronary angioplasty and stent implantation, restenosis remains common and its outcome difficult to predict. We set out to determine the diagnostic accuracy of electron-beam computed tomography (EBCT) for the non-invasive detection of stent obstruction. In a prospective, blinded investigation, we included 152 coronary artery segments in 117 patients treated with a stent implant. All segments were evaluated by a dynamic EBCT study that depicted contrast bolus passage distal to the stent and a CT angiographic study of the entire coronary arteries. It was found that delayed contrast enhancement in the distal segment correlated with angiographic stent obstruction (Spearman's rank correlation, P=0.008), while all other indicators of stent occlusion did not correlate with angiographic diagnosis. However, direct comparison of patients with obstruction of less vs. more than 75% of luminal diameter did not yield any statistically significant differences of distal enhancement delay, and for the detection of >90% occlusion, the sensitivity was 72% at a specificity of 60%. Although delayed contrast enhancement distal to the stent upon EBCT did correlate with angiographical obstruction, the correlation did not suffice to appear clinically satisfactory.

Original languageEnglish (US)
Pages (from-to)1341-1347
Number of pages7
JournalEuropean Radiology
Volume14
Issue number8
StatePublished - Aug 2004
Externally publishedYes

Keywords

  • Cardiac imaging
  • Coronary vessels
  • Electron-beam computed tomography
  • Stents

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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  • Cite this

    Knollmann, F. D., Möller, J., Gebert, A., Bethge, C., & Felix, R. (2004). Assessment of coronary artery stent patency by electron-beam CT. European Radiology, 14(8), 1341-1347.