Assessment of coronary artery stent patency by electron-beam CT

Friedrich D Knollmann, Jörg Möller, Axel Gebert, Christian Bethge, Roland Felix

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Following coronary angioplasty and stent implantation, restenosis remains common and its outcome difficult to predict. We set out to determine the diagnostic accuracy of electron-beam computed tomography (EBCT) for the non-invasive detection of stent obstruction. In a prospective, blinded investigation, we included 152 coronary artery segments in 117 patients treated with a stent implant. All segments were evaluated by a dynamic EBCT study that depicted contrast bolus passage distal to the stent and a CT angiographic study of the entire coronary arteries. It was found that delayed contrast enhancement in the distal segment correlated with angiographic stent obstruction (Spearman's rank correlation, P=0.008), while all other indicators of stent occlusion did not correlate with angiographic diagnosis. However, direct comparison of patients with obstruction of less vs. more than 75% of luminal diameter did not yield any statistically significant differences of distal enhancement delay, and for the detection of >90% occlusion, the sensitivity was 72% at a specificity of 60%. Although delayed contrast enhancement distal to the stent upon EBCT did correlate with angiographical obstruction, the correlation did not suffice to appear clinically satisfactory.

Original languageEnglish (US)
Pages (from-to)1341-1347
Number of pages7
JournalEuropean Radiology
Volume14
Issue number8
StatePublished - Aug 2004
Externally publishedYes

Keywords

  • Cardiac imaging
  • Coronary vessels
  • Electron-beam computed tomography
  • Stents

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Assessment of coronary artery stent patency by electron-beam CT'. Together they form a unique fingerprint.

Cite this