Assessing mucosal immunity with new concepts and innovative, time-honored strategies

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A healthy mucosal immune system prevents numerous diseases whether they are caused by pathogens or faulty tolerance to non-pathogenic antigens. Some methods for assessing immune responses have not changed for decades but have been applied in conjunction with new strategies. New methods have been developed recently that improve on existing mouse models and allowfor assessment of cellular and molecular pathways that are involved inmucosal immune responses. Reviewed here are components of the mucosal immune system with attention paid to the gut-associated lymphoid tissue and some of the new methods for assessing immune responses.

Original languageEnglish (US)
JournalNutrition Reviews
Volume67
Issue numberSUPPL. 2
DOIs
StatePublished - Nov 2009

Keywords

  • GALT assessment methods
  • Humanized immune system
  • Mouse models
  • Mucosal immunity
  • Toll-like receptors

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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