Abstract
A healthy mucosal immune system prevents numerous diseases whether they are caused by pathogens or faulty tolerance to non-pathogenic antigens. Some methods for assessing immune responses have not changed for decades but have been applied in conjunction with new strategies. New methods have been developed recently that improve on existing mouse models and allowfor assessment of cellular and molecular pathways that are involved inmucosal immune responses. Reviewed here are components of the mucosal immune system with attention paid to the gut-associated lymphoid tissue and some of the new methods for assessing immune responses.
| Original language | English (US) |
|---|---|
| Journal | Nutrition Reviews |
| Volume | 67 |
| Issue number | SUPPL. 2 |
| DOIs | |
| State | Published - Nov 2009 |
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Keywords
- GALT assessment methods
- Humanized immune system
- Mouse models
- Mucosal immunity
- Toll-like receptors
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
Cite this
Assessing mucosal immunity with new concepts and innovative, time-honored strategies. / Erickson, Kent L; Hubbard, Neil.
In: Nutrition Reviews, Vol. 67, No. SUPPL. 2, 11.2009.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Assessing mucosal immunity with new concepts and innovative, time-honored strategies
AU - Erickson, Kent L
AU - Hubbard, Neil
PY - 2009/11
Y1 - 2009/11
N2 - A healthy mucosal immune system prevents numerous diseases whether they are caused by pathogens or faulty tolerance to non-pathogenic antigens. Some methods for assessing immune responses have not changed for decades but have been applied in conjunction with new strategies. New methods have been developed recently that improve on existing mouse models and allowfor assessment of cellular and molecular pathways that are involved inmucosal immune responses. Reviewed here are components of the mucosal immune system with attention paid to the gut-associated lymphoid tissue and some of the new methods for assessing immune responses.
AB - A healthy mucosal immune system prevents numerous diseases whether they are caused by pathogens or faulty tolerance to non-pathogenic antigens. Some methods for assessing immune responses have not changed for decades but have been applied in conjunction with new strategies. New methods have been developed recently that improve on existing mouse models and allowfor assessment of cellular and molecular pathways that are involved inmucosal immune responses. Reviewed here are components of the mucosal immune system with attention paid to the gut-associated lymphoid tissue and some of the new methods for assessing immune responses.
KW - GALT assessment methods
KW - Humanized immune system
KW - Mouse models
KW - Mucosal immunity
KW - Toll-like receptors
UR - http://www.scopus.com/inward/record.url?scp=75349091437&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=75349091437&partnerID=8YFLogxK
U2 - 10.1111/j.1753-4887.2009.00238.x
DO - 10.1111/j.1753-4887.2009.00238.x
M3 - Article
C2 - 19906221
AN - SCOPUS:75349091437
VL - 67
JO - Nutrition Reviews
JF - Nutrition Reviews
SN - 0029-6643
IS - SUPPL. 2
ER -