Assembly and functions of the spindle pole body in budding yeast

Mark Winey, Breck Byers

Research output: Contribution to journalReview article

72 Scopus citations

Abstract

The spindle pole body (SPB) serves as the centrosome in yeast and in a variety of other lower eukaryotes. In Saccharomyces cerevisiae, this organelle controls the assembly of all microtubules in the cell, acting not only as a pole of the mitotic or meiotic spindle but also as the site from which cytoplasmic microtubules emanate. The distinctive structure of the SPB has permitted definition of discrete stages in its duplication and behavior at all stages of the yeast life cycle. In association with genetic analyses, studies of the yeast SPB are providing insights into the mechanisms that control centrosomal behavior in this model eukaryote.

Original languageEnglish (US)
Pages (from-to)300-304
Number of pages5
JournalTrends in Genetics
Volume9
Issue number9
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Genetics

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