Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature, and frequency

A. N. DeMaria, Ezra A Amsterdam, L. A. Vismara, A. Neumann, D. T. Mason

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Abstract

Ambulatory monitoring and maximal treadmill exercise were compared in 40 normal subjects and 31 patients with mitral prolapse. A variable arrhythmia spectrum was observed in prolapse during monitoring: premature ventricular contractions in 18 (58%), supraventricular arrhythmias in 11 (35%), and bradyarrhythmias in 9 (29%). Significantly less arrhythmias occurred in normal subjects during monitoring: 10 (25%, P>0.001), 3 (8%, P<0.001), 4 (10%, p<0.05), and 2 (5%, P<0.02), respectively. In patients with prolapse, arrhythmias occurred on resting electrocardiogram (ECG), 35% premature ventricular contractions, 6% supraventricular arrhythmias, and 10% bradyarrhythmias, and on treadmill exercise, 45%, 10%, and 3%; therefore, ambulatory monitoring was the most sensitive method of arrhythmia detection. No correlation existed between clinical features of prolapse and arrhythmias. Thus, arrhythmias occur in most patients with mitral prolapse, are not predictable by clinical characteristics, comprise a spectrum of ventricular and supraventricular tachyarrhythmias and bradyarrhythmias, and are best detected by ambulatory ECG monitoring.

Original languageEnglish (US)
Pages (from-to)656-660
Number of pages5
JournalAnnals of Internal Medicine
Volume84
Issue number6
StatePublished - 1976

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Mitral Valve Prolapse
Cardiac Arrhythmias
Prolapse
Ambulatory Monitoring
Bradycardia
Ventricular Premature Complexes
Electrocardiography
Exercise
Tachycardia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

DeMaria, A. N., Amsterdam, E. A., Vismara, L. A., Neumann, A., & Mason, D. T. (1976). Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature, and frequency. Annals of Internal Medicine, 84(6), 656-660.

Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature, and frequency. / DeMaria, A. N.; Amsterdam, Ezra A; Vismara, L. A.; Neumann, A.; Mason, D. T.

In: Annals of Internal Medicine, Vol. 84, No. 6, 1976, p. 656-660.

Research output: Contribution to journalArticle

DeMaria, AN, Amsterdam, EA, Vismara, LA, Neumann, A & Mason, DT 1976, 'Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature, and frequency', Annals of Internal Medicine, vol. 84, no. 6, pp. 656-660.
DeMaria, A. N. ; Amsterdam, Ezra A ; Vismara, L. A. ; Neumann, A. ; Mason, D. T. / Arrhythmias in the mitral valve prolapse syndrome. Prevalence, nature, and frequency. In: Annals of Internal Medicine. 1976 ; Vol. 84, No. 6. pp. 656-660.
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