Purpose: The purpose of this study was to analyze the cutaneous sensitivity to a variety of allergens in patients with vernal keratoconjunctivitis (VKC) and to demonstrate the relation between skin response and clinical aspects of the disease. Methods: Twenty patients with vernal kerato-conjunctivitis were randomly chosen from the External Disease and Cornea Sector. They were clinically evaluated and a score ranging from 0 to 20 was applied based on signs,and symptoms on ophthalmic examination. All subjects underwent a skin prick test agains standardized allergens, such as house dust mites D. pteronyssinus, D. farinae, and Blomia tropicalis, as well as allergens from cat, dog, fungi and feather, Results: Seventy-five per'cent of patients, were positive for at least one of the allergens tested. House dust mites were responsible for the majority of the cases (75%), There was a poor correlation between the clinical score and sensitivity to allergens (r= 0.119 for fungi; r= - 0.174 for dog; r= - 0.243 for house dust mites; r= - 0.090 for feather). A significant correlation was found only for cat allergen extract(r= - 0.510; p=0.024) Concluslon: Our study demonstrated poor correlation between cutaneous hypersensitivity tests and clinic finding in patients with vernal keratoconjuntivitis. We concluded, that skin response to inhalant allergens is not a useful test, to identify clinical severity and chronicity of inflammatory process in this disease.
|Original language||English (US)|
|Number of pages||5|
|Journal||Arquivos Brasileiros de Oftalmologia|
|State||Published - Nov 2007|
- Conjunctivitis, allergic
- Skin tests
ASJC Scopus subject areas